PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10567921-10	2000	In both systems, long chain fatty acid-containing Gb(3) isoforms, which are less effective to mediate VT1 cytotoxicity, were found to correlate with higher IFN-alpha-mediated antiviral activity.	globotriaosylceramide	50-55	interferon alpha 2	Homo sapiens	156-165	
10567921-11	2000	Inhibition of Gb(3) synthesis in toto prevented IFN-alpha antiviral activity in all cells.	globotriaosylceramide	14-19	interferon alpha 2	Homo sapiens	48-57	
10567921-12	2000	We propose that the long chain Gb(3) fatty isoforms preferentially remain in the plasma membrane, and by associating with IFNAR1, mediate IFN-alpha antiviral signaling, whereas short chain Gb(3) fatty acid isoforms are preferentially internalized to mediate VT1 cytotoxicity and IFNAR1-dependent IFN-alpha growth inhibition.	globotriaosylceramide	31-36	interferon alpha 2	Homo sapiens	138-147	
10567921-0	2000	Functional significance of globotriaosyl ceramide in interferon-alpha(2)/type 1 interferon receptor-mediated antiviral activity.	globotriaosylceramide	27-49	interferon alpha 2	Homo sapiens	53-99	
10567921-3	2000	Gb(3)-deficient variant cells selected for VT resistance are cross-resistant to interferon-alpha (IFN-alpha)-mediated antiproliferative activity.	globotriaosylceramide	0-5	interferon alpha 2	Homo sapiens	98-107	
10567921-5	2000	The crucial role of Gb(3) for the signal transduction of IFN-alpha-mediated antiviral activity is now reported.	globotriaosylceramide	20-25	interferon alpha 2	Homo sapiens	57-66	
10567921-8	2000	Unlike VT1 cytotoxicity, IFN-alpha-induced Stat1 nuclear translocation was not inhibited when RME was prevented, suggesting that the accessory function of Gb(3) occurs at the plasma membrane.	globotriaosylceramide	155-160	interferon alpha 2	Homo sapiens	25-34