PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30578766-5 2019 Furthermore, glycosphingolipids (particularly globotriaosylceramide) generated from serial ceramide glycosylation were seen to activate cSrc and beta-catenin signaling so as to upregulate METTL3 expression, in turn promoting expression of p53 R273H mutant protein, with consequent drug resistance. globotriaosylceramide 46-67 tumor protein p53 Homo sapiens 239-242 33205006-5 2020 We report herewith that globotriaosylceramide (Gb3) is associated with cSrc kinase in GEMs and plays a crucial role in modulating expression of p53 R273H mutant and drug resistance. globotriaosylceramide 24-45 tumor protein p53 Homo sapiens 144-147