PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30841565-0	2019	NMDA Receptor Signaling Mediates cFos Expression via Top2beta-Induced DSBs in Glioblastoma Cells.	dsbs	70-74	DNA topoisomerase II beta	Homo sapiens	53-61	
33256213-7	2020	Consistent with this, in vivo siRNA-mediated knockdown of topoisomerase II beta, the enzyme responsible for DSB, prior to retrieval, reduced Npas4 promoter-specific H2A.XpS139 and H3K4me3 levels and impaired long-term memory, indicating an indispensable role of DSBs in the memory reconsolidation process.	dsbs	262-266	DNA topoisomerase II beta	Homo sapiens	58-79	
20601956-3	2010	We show that androgen signaling promotes co-recruitment of androgen receptor and topoisomerase II beta (TOP2B) to sites of TMPRSS2-ERG genomic breakpoints, triggering recombinogenic TOP2B-mediated DSBs.	dsbs	197-201	DNA topoisomerase II beta	Homo sapiens	81-102	
20601956-3	2010	We show that androgen signaling promotes co-recruitment of androgen receptor and topoisomerase II beta (TOP2B) to sites of TMPRSS2-ERG genomic breakpoints, triggering recombinogenic TOP2B-mediated DSBs.	dsbs	197-201	DNA topoisomerase II beta	Homo sapiens	104-109	
20601956-3	2010	We show that androgen signaling promotes co-recruitment of androgen receptor and topoisomerase II beta (TOP2B) to sites of TMPRSS2-ERG genomic breakpoints, triggering recombinogenic TOP2B-mediated DSBs.	dsbs	197-201	DNA topoisomerase II beta	Homo sapiens	182-187	
29985428-7	2018	The Topo II catalytic inhibitors ICRF-187 and ICRF-193 reduced the Topo IIbeta mobility and thereby prevented Topo IIbeta recruitment to DSBs.	dsbs	137-141	DNA topoisomerase II beta	Homo sapiens	67-78	
29985428-7	2018	The Topo II catalytic inhibitors ICRF-187 and ICRF-193 reduced the Topo IIbeta mobility and thereby prevented Topo IIbeta recruitment to DSBs.	dsbs	137-141	DNA topoisomerase II beta	Homo sapiens	110-121	
29985428-9	2018	Taken together, these results highlight a novel aspect of Topo IIbeta functions in the cellular response to DSBs.	dsbs	108-112	DNA topoisomerase II beta	Homo sapiens	58-69