PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19650872-6	2009	Substitution of the homologous serine in the MAO-B isoform, i.e. Ser200, with either Glu or Ala does not affect the catalytic activity of the corresponding over-expressed proteins.	Glutamic Acid	85-88	monoamine oxidase B	Homo sapiens	45-50	
9724550-3	1998	Previously, Glu-34 and Tyr-44 of MAO B have been identified as residues which engage in noncovalent interactions with FAD that are required for subsequent covalent FAD binding and generation of catalytic activity.	Glutamic Acid	12-15	monoamine oxidase B	Homo sapiens	33-38	
7840641-5	1995	In MAO B, this region is postulated to consist of a beta 1-sheet-alpha-helix-beta 2-sheet motif which culminates with a Glu at the C-terminal end of the second beta-sheet.	Glutamic Acid	120-123	monoamine oxidase B	Homo sapiens	3-8	
35107654-4	2022	For the MAO-B inhibitor safinamide, recently introduced to the market, an additional inhibition of pathological release of glutamate has been postulated.	Glutamic Acid	123-132	monoamine oxidase B	Homo sapiens	8-13	
31686637-3	2020	The monoamine oxidase B (MAO-B) degrades dopamine, promoting the glutamate accumulation and oxidative stress with the release of free radicals, causing excitotoxicity.	Glutamic Acid	65-74	monoamine oxidase B	Homo sapiens	4-23	
31686637-3	2020	The monoamine oxidase B (MAO-B) degrades dopamine, promoting the glutamate accumulation and oxidative stress with the release of free radicals, causing excitotoxicity.	Glutamic Acid	65-74	monoamine oxidase B	Homo sapiens	25-30	
30160213-9	2019	Among all antiparkinsonian agents, MAOB inhibitors are those with the greatest neuroprotective potential because of inhibition of dopamine metabolism, induction of neurotrophic factors, and, in the case of safinamide, inhibition of glutamate release.	Glutamic Acid	232-241	monoamine oxidase B	Homo sapiens	35-39	
28777756-2	2017	Safinamide is a drug with an innovative mechanism of action, dopaminergic and non-dopaminergic, that includes the reversible inhibition of the monoamine oxidase-B (MAO-B) enzyme and the modulation of excessive glutamate release through the use- and state-dependent blockade of the sodium channels.	Glutamic Acid	210-219	monoamine oxidase B	Homo sapiens	164-169	
17849100-3	2007	In the present study, the system was modified with glutamate oxidase instead of tyramine oxidase to detect L-glutamate sensitively ( approximately 10 nM) and rapidly with high temporal resolution (<1 s).	Glutamic Acid	107-118	monoamine oxidase B	Homo sapiens	80-96	
14697882-11	2004	65 (2001) 129], we have identified three amino acids residues (Phe 423, Glu 427, and Thr 428) that appear to play a role in generating catalytically active MAO B.	Glutamic Acid	72-75	monoamine oxidase B	Homo sapiens	156-161	
14697882-13	2004	Thus, it appears that Phe 423, Glu 427 and Thr 428 do not directly affect the active site, but they could modulate activity through an independent function such as non-covalent binding of FAD during synthesis of the MAO B polypeptide chain.	Glutamic Acid	31-34	monoamine oxidase B	Homo sapiens	216-221