PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26065977-5	2015	Our results show for the first time a strong alteration of neurons morphology and an inhibitory effect of differentiation by itraconazole, probably due to cholesterol trafficking reduction, mTOR and Shh pathways inhibition.	Itraconazole	125-137	sonic hedgehog	Mus musculus	199-202	
30472702-0	2018	Itraconazole Attenuates Peritoneal Fibrosis Through Its Effect on the Sonic Hedgehog Signaling Pathway in Mice.	Itraconazole	0-12	sonic hedgehog	Mus musculus	70-84	
30472702-5	2018	Itraconazole, an anti-fungal agent, was also recently recognized as an inhibitor of the SHH signaling pathway.	Itraconazole	0-12	sonic hedgehog	Mus musculus	88-91	
30472702-12	2018	The expression of the following SHH signaling pathway components was upregulated in the CG group and suppressed by itraconazole treatment: SHH, patched, smoothened, and glioma-associated oncogene transcription factor 1.	Itraconazole	115-127	sonic hedgehog	Mus musculus	32-35	
30472702-12	2018	The expression of the following SHH signaling pathway components was upregulated in the CG group and suppressed by itraconazole treatment: SHH, patched, smoothened, and glioma-associated oncogene transcription factor 1.	Itraconazole	115-127	sonic hedgehog	Mus musculus	139-142	
30472702-16	2018	It also demonstrates that itraconazole treatment has protective effects on peritoneal fibrosis through the regulation of the SHH signaling pathway.	Itraconazole	26-38	sonic hedgehog	Mus musculus	125-128