PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30075232-3	2018	We investigated whether VEGF has a neuroprotective role by inhibiting its binding to receptor Flk-1 by itraconazole (ITZ).	Itraconazole	103-115	kinase insert domain receptor	Rattus norvegicus	94-99	
30075232-3	2018	We investigated whether VEGF has a neuroprotective role by inhibiting its binding to receptor Flk-1 by itraconazole (ITZ).	Itraconazole	117-120	kinase insert domain receptor	Rattus norvegicus	94-99	
28666022-10	2017	Quantitative RT-PCR showed significantly lower expression of VEGFR2 mRNA in the RPE-choroid complexes of itraconazole-injected eyes than those of BSS-injected eyes on days 7 and 14 (p = 0.003 and p = 0.006).	Itraconazole	105-117	kinase insert domain receptor	Rattus norvegicus	61-67	
28666022-11	2017	Western blots indicated that VEGFR2 was downregulated after itraconazole treatment.	Itraconazole	60-72	kinase insert domain receptor	Rattus norvegicus	29-35	
28666022-14	2017	Itraconazole had anti-angiogenic activity along with the reduction of VEGFR2 and VEGF levels.	Itraconazole	0-12	kinase insert domain receptor	Rattus norvegicus	70-76	
32649934-4	2020	By blocking VEGF/VEGFR-2 binding via pre-treatment with itraconazole we demonstrated that animals" condition was deteriorated soon at 1-2 h post-PNV exposure concurrently with decreased expression of VEGF, BBB-associated proteins, ZO-1, beta-catenin, laminin, P-gp (P-glycoprotein), Neu-N (neuron"s viability marker) and MAPKphosphorylated-p38, while phosphorylated-ERK and Src pathways were increased.	Itraconazole	56-68	kinase insert domain receptor	Rattus norvegicus	17-24