PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24508512-0 2014 A-ring modified steroidal azoles retaining similar potent and slowly reversible CYP17A1 inhibition as abiraterone. Azoles 26-32 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 80-87 31330226-2 2019 The aim of this study was to mechanistically investigate the endocrine disrupting potential of four commonly used azole antifungal drugs; clotrimazole, miconazole, ketoconazole and fluconazole in vitro using the H295R cell assay and two recombinant, CYP17A1 and CYP19A1 (aromatase), assays. Azoles 114-119 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 250-257 12773039-6 2003 A model that permits hydrogen bond interaction between the azole functionality on ring D and the enzyme is consistent with experimental deductions for type II CYP17 inhibitors where a sixth ligating atom interacts with Fe(II) of heme. Azoles 59-64 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 159-164