PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10947162-9	2000	Inhibition of protein kinase C with H7 or bisindolylmaleimide prevented TNF secretion and ERK 1/2 activation by LPSa.	1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine	36-38	tumor necrosis factor	Mus musculus	72-75	
8732044-0	1995	Protein kinase C inhibitor H-7 blocks effects of tumor necrosis factor on bone cells.	1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine	27-30	tumor necrosis factor	Mus musculus	49-70	
8732044-6	1995	These TNF-induced actions were blocked by simultaneous addition of H-7 (5-20 mumol .	1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine	67-70	tumor necrosis factor	Mus musculus	6-9	
7527452-7	1994	Finally, we have demonstrated that H7 inhibited the enhancement of nuclear protein binding to the NFkB consensus sequence in the promoter of the TNF alpha gene that we observed in LPL-treated macrophages.	1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine	35-37	tumor necrosis factor	Mus musculus	145-154	
7680963-3	1993	Stimulation of VCAM-1 expression by TNF may be diminished by ionomycin as well as by inhibitors of protein kinases (H-7 and sangivamycin).	1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine	116-119	tumor necrosis factor	Mus musculus	36-39	
1658014-4	1991	We found that the TNF-generated signal is inhibited by H-7 and sangivamycin, but not by staurosporine.	1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine	55-58	tumor necrosis factor	Mus musculus	18-21