PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8258686-4 1993 Our study demonstrated that IL-2, IL-4, and IL-6-stimulation of IgM secretion by SKW6.4 cells was inhibited by either the serine/threonine kinase inhibitor, 1-(5-isoquinolinesulfonyl)-2-methylpiperizine dihydrochloride (H7) or the tyrosine kinase inhibitor, genistein. 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine 220-222 interleukin 4 Homo sapiens 34-38 12356680-4 2002 This latter response to IL-10 was strictly dependent on the levels of expression of IL-10R1, which were in fact significantly increased by IL-4 in cultured neutrophils via a signaling pathway sensitive to the serine/threonine kinase inhibitor H-7. 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine 243-246 interleukin 4 Homo sapiens 139-143 9250823-5 1997 The inhibitory effect of IL4 on the expression of CD21 and its augmentary effect on the expression of CD23 was abrogated by H7 (1-(5-Isoquinolinylsulfonyl)-2-methylpiperazine), an inhibitor of serine protein kinase. 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine 128-174 interleukin 4 Homo sapiens 25-28