PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10882187-6 2000 Pretreatment with 10(-6) M of PKC inhibitor, 1-(5-isoquinolinesulfonyl-methyl) piperazine (H7), blocked Ang II-induced hypertrophy and PGF2alpha release. 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine 91-93 angiotensinogen Rattus norvegicus 104-110 15694920-9 2005 Pressure application of H-7 alone decreased the basal firing activity of angiotensin II-sensitive neurons in SHR but not in WKY. 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine 24-27 angiotensinogen Rattus norvegicus 73-87 11841996-4 2002 ANG II-induced contraction of rat IAS smooth muscle and SMC was attenuated by tyrosine kinase inhibitors genistein and tyrphostin, protein kinase C (PKC) inhibitor H-7, Ca(2+) channel blocker nicardipine, Rho kinase inhibitor Y-27632 or p(44/42) mitogen-activating protein kinase (MAPK(44/42)) inhibitor PD-98059. 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine 164-167 angiotensinogen Rattus norvegicus 0-6 11841996-5 2002 Combinations of nicardipine and H-7, Y-27632, and PD-98059 caused further attenuation of the ANG II effects. 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine 32-35 angiotensinogen Rattus norvegicus 93-99 8831515-10 1996 Stretch-induced changes in levels of Ang II receptors were inhibited by genistein but not by H-7, staurosporin, and protein kinase C depletion or by BAPTA-AM. 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine 93-96 angiotensinogen Rattus norvegicus 37-43 8632699-6 1996 We observed that PMA (0.1 microM) stimulated ANP release whereas H-7 (10 microM), an inhibitor of PKC in the presence of Ang II, prevented ANP increase. 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine 65-68 angiotensinogen Rattus norvegicus 121-127