PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9861301-9	1998	These responses to ET-1 were abolished by the incubation of myocytes with an ETA receptor antagonist (BQ123) or a protein kinase C (PKC) inhibitor (H-7 or staurosporine).	1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine	148-151	endothelin 1	Rattus norvegicus	19-23	
1314585-4	1992	ET-1-induced suppression of TSH actions were reversed by a C-kinase inhibitor, H-7.	1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine	79-82	endothelin 1	Rattus norvegicus	0-4	
1312437-5	1992	Pertussis toxin and the protein kinase-C inhibitors, H-7 and staurosporine, all of which enhanced adipocyte differentiation of rat adipose precursor cells, partially reversed ET-1 inhibition.	1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine	53-56	endothelin 1	Rattus norvegicus	175-179	
9486138-9	1998	Inhibitors of ets-1 gene expression, such as H-7 and herbimycin A, inhibited the ET-1 induction of collagenase I mRNA.	1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine	45-48	endothelin 1	Rattus norvegicus	81-85	
7630315-2	1995	Jatrophone, staurosporine and H-7, caused graded inhibition of rat portal vein contractions induced by phorbol 12-myristate 13-acetate (PMA), noradrenaline, endothelin-1 or KCl, with IC50s of 86 nM, 13 microM, 11 microM and 9 microM, respectively.	1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine	30-33	endothelin 1	Rattus norvegicus	157-169	
7630315-5	1995	Jatrophone, H-7 and staurosporine caused graded relaxations of preparations contracted with endothelin-1 or PMA with IC50s of 12 and > 1000 microM, 8 and 13 microM and 7 and 12 nM, respectively.	1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine	12-15	endothelin 1	Rattus norvegicus	92-104	
1327578-6	1992	The enhancement of ICa,T by ET-1 was antagonized by protein kinase C inhibitors staurosporine (0.2 microM) and 1-(5-isoquinolinesulfonyl)-2-methylpiperazine (H-7, 20 microM) applied to the pipette solution.	1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine	111-156	endothelin 1	Rattus norvegicus	28-32	
1327578-6	1992	The enhancement of ICa,T by ET-1 was antagonized by protein kinase C inhibitors staurosporine (0.2 microM) and 1-(5-isoquinolinesulfonyl)-2-methylpiperazine (H-7, 20 microM) applied to the pipette solution.	1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine	158-161	endothelin 1	Rattus norvegicus	28-32