PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25465546-7 2015 injections of 4mg of quinagolide, a specific inhibitor of PRL release, from 5 d before drying-off until 13 d after (QN). quinagolide 21-32 prolactin Bos taurus 58-61 31280741-2 2019 Accordingly, the inhibition of PRL secretion by the dopamine agonists quinagolide and cabergoline causes a sharp decline in milk production and could be useful in several critical periods. quinagolide 70-81 prolactin Bos taurus 31-34 26547648-5 2016 Quinagolide reduced milking-induced PRL release and caused a faster decline in milk production. quinagolide 0-11 prolactin Bos taurus 36-39 26547648-15 2016 In addition, quinagolide improved the resistance to intramammary infection, suggesting that PRL inhibition could be an alternative strategy for facilitating drying-off. quinagolide 13-24 prolactin Bos taurus 92-95 26387019-1 2015 It has been previously shown that the long-term inhibition of milking-induced prolactin (PRL) release by quinagolide (QN), a dopamine agonist, reduces milk yield in dairy cows. quinagolide 105-116 prolactin Bos taurus 78-87 26387019-1 2015 It has been previously shown that the long-term inhibition of milking-induced prolactin (PRL) release by quinagolide (QN), a dopamine agonist, reduces milk yield in dairy cows. quinagolide 105-116 prolactin Bos taurus 89-92 26387019-1 2015 It has been previously shown that the long-term inhibition of milking-induced prolactin (PRL) release by quinagolide (QN), a dopamine agonist, reduces milk yield in dairy cows. quinagolide 118-120 prolactin Bos taurus 78-87 26387019-1 2015 It has been previously shown that the long-term inhibition of milking-induced prolactin (PRL) release by quinagolide (QN), a dopamine agonist, reduces milk yield in dairy cows. quinagolide 118-120 prolactin Bos taurus 89-92 26298751-1 2015 In previous studies, our team showed that the inhibition of prolactin (PRL) secretion by the dopamine agonist quinagolide reduces milk production in dairy cows. quinagolide 110-121 prolactin Bos taurus 60-69 26298751-1 2015 In previous studies, our team showed that the inhibition of prolactin (PRL) secretion by the dopamine agonist quinagolide reduces milk production in dairy cows. quinagolide 110-121 prolactin Bos taurus 71-74 25465546-9 2015 Quinagolide induced a decrease in PRL concentration in blood on all the injection days. quinagolide 0-11 prolactin Bos taurus 34-37 24881791-7 2014 injections of 4mg of quinagolide, a specific inhibitor of PRL release, from 5d before drying off until 13d after (QN; n=8). quinagolide 21-32 prolactin Bos taurus 58-61 24881791-8 2014 Quinagolide induced a decrease in PRL concentration in blood and in milk and mammary secretions on all the injection days. quinagolide 0-11 prolactin Bos taurus 34-37 22281117-5 2012 In a first experiment, daily injections of the PRL inhibitor quinagolide reduced milking-induced PRL release and induced a faster decline in milk production. quinagolide 61-72 prolactin Bos taurus 47-50 23164222-6 2013 Of those cows, 8 received twice-daily intramuscular injections (2 mg per injection) of quinagolide, a specific inhibitor of PRL release, from 4 d before drying-off to 3 d after (Quin). quinagolide 87-98 prolactin Bos taurus 124-127 23164222-10 2013 Quinagolide reduced basal serum PRL concentrations on all injection days as well as PRL released in blood during milking. quinagolide 0-11 prolactin Bos taurus 32-35 22281117-5 2012 In a first experiment, daily injections of the PRL inhibitor quinagolide reduced milking-induced PRL release and induced a faster decline in milk production. quinagolide 61-72 prolactin Bos taurus 97-100 22281117-9 2012 The inhibition of milk production by quinagolide was maintained in the udder half that was milked 2x but not in the udder half milked 1x, suggesting that the response to PRL is modulated at the gland level. quinagolide 37-48 prolactin Bos taurus 170-173 22192196-0 2012 Mammary cell activity and turnover in dairy cows treated with the prolactin-release inhibitor quinagolide and milked once daily. quinagolide 94-105 prolactin Bos taurus 66-75 22192196-2 2012 injections of 1mg of quinagolide, a suppressor of PRL release, for 9 wk, whereas 4 control cows received the vehicle (water) only. quinagolide 21-32 prolactin Bos taurus 50-53 22192196-12 2012 In conclusion, the reduction in milk yield after chronic administration of the PRL-release inhibitor quinagolide is associated with a reduction in mammary cell activity, survival, and proliferation in lactating dairy cows. quinagolide 101-112 prolactin Bos taurus 79-82 21338795-2 2011 To assess the effect of the long-term inhibition of PRL release in lactating dairy cows, 5 Holstein cows in early lactation received daily intramuscular injections of 1mg of the PRL-release inhibitor quinagolide for 9 wk. quinagolide 200-211 prolactin Bos taurus 178-181 21338795-6 2011 The daily injections of quinagolide reduced milking-induced PRL release but not the basal PRL concentration. quinagolide 24-35 prolactin Bos taurus 60-63 21338795-13 2011 In conclusion, the chronic administration of the PRL-release inhibitor quinagolide decreases milk production in dairy cows. quinagolide 71-82 prolactin Bos taurus 49-52