PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28240161-6	2017	Meanwhile, we confirmed that DHM showed antitumor activity by regulating the activation of the p53-dependent pathways (MDM2, P-MDM2, BAX and Bcl-2).	Dihydromorphine	29-32	tumor protein p53	Homo sapiens	95-98	
28240161-5	2017	It is very interesting that we found DHM could regulate TGF-beta signal pathway and which has a crosstalk with P53, Smad3 and P-Smad2/3 proteins.	Dihydromorphine	37-40	tumor protein p53	Homo sapiens	111-114	
28240161-7	2017	These findings defined and supported a novel mechanism that DHM could induce cell apoptosis by reducing TGF-beta via p53 signal pathway in HepG2 cells.	Dihydromorphine	60-63	tumor protein p53	Homo sapiens	117-120