PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
14622273-9	2003	The observation that the KI value for mutant AChE in which Ala replaced Trp286 is similar to that for wild-type BChE, further confirms our hypothesis.	Alanine	59-62	acetylcholinesterase (Cartwright blood group)	Homo sapiens	45-49	
26200472-6	2015	Replacement of hAChE residues known to be essential for its interaction with Fas with alanine, in this peptide, resulted in almost complete loss of binding to Fas.	Alanine	86-93	acetylcholinesterase (Cartwright blood group)	Homo sapiens	15-20	
12498995-1	2002	OBJECTIVE: a) To evaluate acetylcholinesterase (AChE) activities in erythrocyte membranes from phenylketonuric (PKU) patients and controls and to correlate with their plasma phenylalanine (Phe), tyrosine (Tyr), alanine (Ala) and dopamine (DA) levels.	Alanine	180-187	acetylcholinesterase (Cartwright blood group)	Homo sapiens	26-46	
12498995-1	2002	OBJECTIVE: a) To evaluate acetylcholinesterase (AChE) activities in erythrocyte membranes from phenylketonuric (PKU) patients and controls and to correlate with their plasma phenylalanine (Phe), tyrosine (Tyr), alanine (Ala) and dopamine (DA) levels.	Alanine	180-187	acetylcholinesterase (Cartwright blood group)	Homo sapiens	48-52	
12498995-1	2002	OBJECTIVE: a) To evaluate acetylcholinesterase (AChE) activities in erythrocyte membranes from phenylketonuric (PKU) patients and controls and to correlate with their plasma phenylalanine (Phe), tyrosine (Tyr), alanine (Ala) and dopamine (DA) levels.	Alanine	220-223	acetylcholinesterase (Cartwright blood group)	Homo sapiens	26-46	
12498995-1	2002	OBJECTIVE: a) To evaluate acetylcholinesterase (AChE) activities in erythrocyte membranes from phenylketonuric (PKU) patients and controls and to correlate with their plasma phenylalanine (Phe), tyrosine (Tyr), alanine (Ala) and dopamine (DA) levels.	Alanine	220-223	acetylcholinesterase (Cartwright blood group)	Homo sapiens	48-52	
12498995-2	2002	b) To determine the in vitro effects of Phe, Ala and Phe plus Ala on their AChE activities.	Alanine	45-48	acetylcholinesterase (Cartwright blood group)	Homo sapiens	75-79	
12498995-2	2002	b) To determine the in vitro effects of Phe, Ala and Phe plus Ala on their AChE activities.	Alanine	62-65	acetylcholinesterase (Cartwright blood group)	Homo sapiens	75-79	
12498995-8	2002	Ala reversed the inhibited AChE by Phe in erythrocyte membranes from healthy children to control values, whereas no reverse effect was observed on the enzyme activity from PKU patients.	Alanine	0-3	acetylcholinesterase (Cartwright blood group)	Homo sapiens	27-31	
12132693-0	2002	Alanine reverses the inhibitory effect of phenylalanine on acetylcholinesterase activity.	Alanine	0-7	acetylcholinesterase (Cartwright blood group)	Homo sapiens	59-79	
1517212-2	1992	Evidence for the involvement of Ser-203, His-447, and Glu-334 in the catalytic triad of human acetylcholinesterase was provided by substitution of these amino acids by alanine residues.	Alanine	168-175	acetylcholinesterase (Cartwright blood group)	Homo sapiens	94-114	
12132693-1	2002	The aim of this work was to evaluate, in vitro, the effect of L-alanine (Ala) on suckling rat brain acetylcholinesterase (AChE) and on eel Electrophorus electricus pure AChE inhibited by L-phenylalanine (Phe) as well as to investigate whether Phe or Ala is a competitive inhibitor or an effector of the enzyme.	Alanine	250-253	acetylcholinesterase (Cartwright blood group)	Homo sapiens	169-173	
12132693-2	2002	AChE activity was determined in brain homogenates and in the pure enzyme after 1 h preincubation with 1.2 mM of Phe or Ala as well as with Phe plus Ala.	Alanine	119-122	acetylcholinesterase (Cartwright blood group)	Homo sapiens	0-4	
12132693-4	2002	Ala reversed completely the inhibited AChE by Phe (18-20% in 500-600 microM substrate, p<0.01).	Alanine	0-3	acetylcholinesterase (Cartwright blood group)	Homo sapiens	38-42	
11904227-8	2002	Thus a single amino acid substitution in the pi-cation site, from the aromatic tyrosine of B. fasciatus AChE to the alanine of BuChE, caused AChE to behave like BuChE.	Alanine	116-123	acetylcholinesterase (Cartwright blood group)	Homo sapiens	104-108	
11904227-8	2002	Thus a single amino acid substitution in the pi-cation site, from the aromatic tyrosine of B. fasciatus AChE to the alanine of BuChE, caused AChE to behave like BuChE.	Alanine	116-123	acetylcholinesterase (Cartwright blood group)	Homo sapiens	141-145	
3306451-6	1987	Acetylcholinesterase more slowly cleaved the C-terminal alanine residue from the peptide to yield LWMRF.	Alanine	56-63	acetylcholinesterase (Cartwright blood group)	Homo sapiens	0-20