PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19225000-6 2009 Alanine substitutions for LANA residues (1068)LKK(1070) and (1125)SHP(1127) severely impaired chromosome binding but did not reduce the other C-terminal LANA functions of self-association or DNA binding. Alanine 0-7 LANA Human gammaherpesvirus 8 26-30 26420481-6 2015 As expected, LANA mutants with alanine or glutamate substitutions in the central, peripheral, or lateral portions of the positive patch maintained the ability to bind DNA by EMSA. Alanine 31-38 LANA Human gammaherpesvirus 8 13-17