PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21709005-10	2011	RESULTS: During the 72-h period after MNU exposure, the caspase-3 expression increased and the LC3 and Atg5 expression decreased, indicating increased levels of apoptosis and decreased levels of autophagy, as compared with the MNU-unexposed control mouse retina.	Methylnitrosourea	38-41	caspase 3	Mus musculus	56-65	
22645991-11	2012	A single systemic administration of MNU (70 mg/kg) increased intracellular levels of p53, PARP, FasR, caspase 3 active, which was followed by destructive changes in retina with sings of apoptosis of photoreceptors.	Methylnitrosourea	36-39	caspase 3	Mus musculus	102-111	
21240523-0	2011	Caspase-3-independent photoreceptor degeneration by N-methyl-N-nitrosourea (MNU) induces morphological and functional changes in the mouse retina.	Methylnitrosourea	52-74	caspase 3	Mus musculus	0-9	
21240523-13	2011	CONCLUSION: MNU leads to the dose-dependent degeneration of photoreceptor cells in mice by caspase-3-independent pathways and is, therefore, a suitable model to study retinal degeneration in an animal model.	Methylnitrosourea	12-15	caspase 3	Mus musculus	91-100	
21240523-0	2011	Caspase-3-independent photoreceptor degeneration by N-methyl-N-nitrosourea (MNU) induces morphological and functional changes in the mouse retina.	Methylnitrosourea	76-79	caspase 3	Mus musculus	0-9	
13679151-8	2003	While caspase-3 was induced in Mgmt(-/-)Mlh1(+/+) cells after treatment with MNU, no induction occurred in Mgmt(-/-)Mlh1(+/-) cells or in Mgmt(-/-)Mlh1(-/-) cells.	Methylnitrosourea	77-80	caspase 3	Mus musculus	6-15