PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31179317-7	2019	One day following MNU administration, phosphorylation of the cell death-associated signalling proteins c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (p38) increased, while the apoptosis-related proteins, full-length poly(ADP-ribose) polymerase (PARP) and apoptosis-inducing factor (AIF), were depleted.	Methylnitrosourea	18-21	poly (ADP-ribose) polymerase 1	Rattus norvegicus	270-274	
31179317-7	2019	One day following MNU administration, phosphorylation of the cell death-associated signalling proteins c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (p38) increased, while the apoptosis-related proteins, full-length poly(ADP-ribose) polymerase (PARP) and apoptosis-inducing factor (AIF), were depleted.	Methylnitrosourea	18-21	poly (ADP-ribose) polymerase 1	Rattus norvegicus	241-268	
18019406-0	2007	PARP inhibitors accelerate N-methyl-N-nitrosourea-induced cataractogenesis in Sprague-Dawley rats.	Methylnitrosourea	27-49	poly (ADP-ribose) polymerase 1	Rattus norvegicus	0-4	
18019406-11	2007	CONCLUSION: The PARP inhibitors nicotinamide and 3-aminobenzamide accelerated MNU-induced cataractogenesis.	Methylnitrosourea	78-81	poly (ADP-ribose) polymerase 1	Rattus norvegicus	16-20	
16168987-0	2006	Nicotinamide blocks N-methyl-N-nitrosourea-induced photoreceptor cell apoptosis in rats through poly (ADP-ribose) polymerase activity and Jun N-terminal kinase/activator protein-1 pathway inhibition.	Methylnitrosourea	20-42	poly (ADP-ribose) polymerase 1	Rattus norvegicus	96-124	
17137578-0	2007	Poly (ADP-ribose) polymerase inhibitor 3-aminobenzamide rescues N-methyl-N-nitrosourea-induced photoreceptor cell apoptosis in Sprague-Dawley rats through preservation of nuclear factor-kappaB activity.	Methylnitrosourea	64-86	poly (ADP-ribose) polymerase 1	Rattus norvegicus	0-28	
17137578-1	2007	The activation of poly (ADP-ribose) polymerase (PARP) plays a pivotal role in mediating N-methyl-N-nitrosourea (MNU)-induced photoreceptor cell apoptosis.	Methylnitrosourea	88-110	poly (ADP-ribose) polymerase 1	Rattus norvegicus	18-46	
17137578-1	2007	The activation of poly (ADP-ribose) polymerase (PARP) plays a pivotal role in mediating N-methyl-N-nitrosourea (MNU)-induced photoreceptor cell apoptosis.	Methylnitrosourea	112-115	poly (ADP-ribose) polymerase 1	Rattus norvegicus	18-46