PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9447233-5 1997 To identify the mechanism responsible for the less pronounced phenotype of the second complementation group, we characterized the persistence of MNU-induced O6-methylguanine (O6-meGua) and mutation induction at the hypoxanthine guanine phosphoribosyl-transferase (HPRT) locus. Methylnitrosourea 145-148 hypoxanthine phosphoribosyltransferase 1 Homo sapiens 215-262 9447233-5 1997 To identify the mechanism responsible for the less pronounced phenotype of the second complementation group, we characterized the persistence of MNU-induced O6-methylguanine (O6-meGua) and mutation induction at the hypoxanthine guanine phosphoribosyl-transferase (HPRT) locus. Methylnitrosourea 145-148 hypoxanthine phosphoribosyltransferase 1 Homo sapiens 264-268 2484616-6 1989 Sodium arsenite at relatively nontoxic concentrations (5 microM for 24 h or 10 microM for 3 h) is comutagenic with N-methyl-N-nitrosourea (MMU) at the hprt locus in V79 cells. Methylnitrosourea 115-137 hypoxanthine phosphoribosyltransferase 1 Homo sapiens 151-155 8472339-0 1993 Specificity of mutations induced by N-methyl-N-nitrosourea in a cDNA of the hprt gene. Methylnitrosourea 36-58 hypoxanthine phosphoribosyltransferase 1 Homo sapiens 76-80 8472339-3 1993 Mutational sequence alterations were determined for 53 independent mutations induced by MNU in a cDNA of the human hprt gene, which is stably integrated into chromosomes of the mouse cell line VH12. Methylnitrosourea 88-91 hypoxanthine phosphoribosyltransferase 1 Homo sapiens 115-119 28622829-5 2017 A hormetic-style dose-response following a 24h exposure to the alkylating agent N-methyl-N-nitrosourea (MNU) was observed in a previous study for HPRT mutagenesis in the human lymphoblastoid cell line AHH-1. Methylnitrosourea 80-102 hypoxanthine phosphoribosyltransferase 1 Homo sapiens 146-150 28622829-5 2017 A hormetic-style dose-response following a 24h exposure to the alkylating agent N-methyl-N-nitrosourea (MNU) was observed in a previous study for HPRT mutagenesis in the human lymphoblastoid cell line AHH-1. Methylnitrosourea 104-107 hypoxanthine phosphoribosyltransferase 1 Homo sapiens 146-150