PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32922479-2 2020 The reaction of oximoinoketone intermediate with ten different aromatic aldehyde and ammonium acetate in refluxing acetic acid condition give imidazole derived product, the IL-1beta inhibitory assay were performed on Human PBMCs (peripheral blood mononuclear cells) using an enzyme-linked immunosorbent assay (ELISA) kit and then in computational part the binding mode of the best compound was accomplished by docking in Crystal structure of p38 MAP kinase (PDB ID: 1A9U) compared with SB202190 as standard drug. oximoinoketone 16-30 interleukin 1 alpha Homo sapiens 173-181