PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3233222-3 1988 Membranes composed of a mixture of phosphatidylcholine (PC) and positively charged lipids like stearylamine, sphingosine, or hexadecyltrimethylammonium bromide caused a more than 1000-fold increase of the rate of prothrombin activation. stearylamine 95-107 coagulation factor II, thrombin Homo sapiens 213-224 3162382-6 1988 Introduction of stearylamine in membranes containing phosphatidyl-beta-lactate (PLac) causes considerable inhibition of their prothrombin-converting activity. stearylamine 16-28 coagulation factor II, thrombin Homo sapiens 126-137 3233222-7 1988 Calcium ions strongly inhibited prothrombin activation on vesicles composed of PC and stearylamine (80/20 M/M), which indicates that the regions of prothrombin and/or factor Xa containing gamma-carboxyglutamic acid (gla) are important for the interaction of these proteins with positively charged membranes. stearylamine 86-98 coagulation factor II, thrombin Homo sapiens 32-43