PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26498361-1	2016	OBJECTIVES: This review stated the possible application of the active components of licorice, glycyrrhizin (GL) and glycyrrhetinic acid (GA), in rheumatoid arthritis (RA) treatment based on the cyclooxygenase (COX)-2/thromboxane A2 (TxA2) pathway.	Glycyrrhetinic Acid	116-135	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	194-216	
26498361-1	2016	OBJECTIVES: This review stated the possible application of the active components of licorice, glycyrrhizin (GL) and glycyrrhetinic acid (GA), in rheumatoid arthritis (RA) treatment based on the cyclooxygenase (COX)-2/thromboxane A2 (TxA2) pathway.	Glycyrrhetinic Acid	137-139	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	194-216	
26498361-3	2016	RESULTS: The active components of licorice GL and GA exert the potential anti-inflammatory effects through, at least in part, suppressing COX-2 and its downstream product TxA2.	Glycyrrhetinic Acid	50-52	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	138-143	
26498361-7	2016	CONCLUSIONS: The active components of licorice, GL and GA, could not only potentiate the therapeutic effects but also decrease the adverse effects of NSAIDs or DMARDs through suppressing the COX-2/TxA2 pathway during treatment course of RA.	Glycyrrhetinic Acid	55-57	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	191-196	
21426233-7	2011	Accordingly, 18beta-glycyrrhetic acid prevented HMGB1-dependent COX2 expression and cluster formation in primary cultures of human macrophages.	Glycyrrhetinic Acid	13-37	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	64-68	
33505216-9	2021	Moreover, GA is capable of blocking prostaglandin-E2 synthesis via blockade of cyclooxygenase- (COX-) 2 resulting in concurrent augmentation nitric oxide production through the enhancement of iNOS2 mRNA secretion in Leishmania-infected macrophages.	Glycyrrhetinic Acid	10-12	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	79-103