PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23782349-3 2013 Here, we developed N-hydroxyguanidine NO donor drugs that were protected against spontaneous NO release by linkage to glutamyl adducts that could be cleaved by gamma-glutamyl transpeptidase (gamma-GT), found predominantly in renal tissue. hydroxyguanidine 19-37 inactive glutathione hydrolase 2 Homo sapiens 160-189 23782349-3 2013 Here, we developed N-hydroxyguanidine NO donor drugs that were protected against spontaneous NO release by linkage to glutamyl adducts that could be cleaved by gamma-glutamyl transpeptidase (gamma-GT), found predominantly in renal tissue. hydroxyguanidine 19-37 inactive glutathione hydrolase 2 Homo sapiens 191-199 23322269-1 2013 This communication describes the synthesis of a new class of N-hydroxyguanidine (NHG) pro-drugs which release nitric oxide (NO), triggered by the action of gamma-glutamyl transpeptidase (gamma-GT), and have potential for the treatment of acute renal injury/failure (ARI/ARF). hydroxyguanidine 61-79 inactive glutathione hydrolase 2 Homo sapiens 156-185 23322269-1 2013 This communication describes the synthesis of a new class of N-hydroxyguanidine (NHG) pro-drugs which release nitric oxide (NO), triggered by the action of gamma-glutamyl transpeptidase (gamma-GT), and have potential for the treatment of acute renal injury/failure (ARI/ARF). hydroxyguanidine 61-79 inactive glutathione hydrolase 2 Homo sapiens 187-195 23322269-1 2013 This communication describes the synthesis of a new class of N-hydroxyguanidine (NHG) pro-drugs which release nitric oxide (NO), triggered by the action of gamma-glutamyl transpeptidase (gamma-GT), and have potential for the treatment of acute renal injury/failure (ARI/ARF). hydroxyguanidine 81-84 inactive glutathione hydrolase 2 Homo sapiens 156-185 23322269-1 2013 This communication describes the synthesis of a new class of N-hydroxyguanidine (NHG) pro-drugs which release nitric oxide (NO), triggered by the action of gamma-glutamyl transpeptidase (gamma-GT), and have potential for the treatment of acute renal injury/failure (ARI/ARF). hydroxyguanidine 81-84 inactive glutathione hydrolase 2 Homo sapiens 187-195