PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8274159-0	1993	Cytochrome P450 dependent N-hydroxylation of a guanidine (debrisoquine), microsomal catalysed reduction and further oxidation of the N-hydroxy-guanidine metabolite to the urea derivative.	hydroxyguanidine	133-152	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	11-15	
8274159-8	1993	Whereas the N-hydroxylation of the guanidine involves the usual monooxygenase activity of cytochrome P450 the resultant N-hydroxyguanidine decouples monooxygenases (cytochrome P450, FMO) and the H2O2 and, above all, O2- thus formed transform the N-hydroxyguanidine further to the corresponding urea derivative.	hydroxyguanidine	120-138	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	101-105	
8274159-8	1993	Whereas the N-hydroxylation of the guanidine involves the usual monooxygenase activity of cytochrome P450 the resultant N-hydroxyguanidine decouples monooxygenases (cytochrome P450, FMO) and the H2O2 and, above all, O2- thus formed transform the N-hydroxyguanidine further to the corresponding urea derivative.	hydroxyguanidine	120-138	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	176-180