PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31733235-7	2020	This effect was blocked by co-exposure to tetramethoxystilbene (30 nM), a selective CYP1B1 inhibitor.	2,4,3',5'-tetramethoxystilbene	42-62	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	84-90	
11719446-3	2001	The inhibition of recombinant human P450 1B1 by 2,4,3",5"-tetramethoxystilbene (TMS) was investigated using either bacterial membranes from a human P450/NADPH-P450 reductase bicistronic expression system or using purified enzymes.	2,4,3',5'-tetramethoxystilbene	48-78	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	36-44	
11719446-3	2001	The inhibition of recombinant human P450 1B1 by 2,4,3",5"-tetramethoxystilbene (TMS) was investigated using either bacterial membranes from a human P450/NADPH-P450 reductase bicistronic expression system or using purified enzymes.	2,4,3',5'-tetramethoxystilbene	80-83	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	36-44	
12628515-7	2003	Further studies with rhapontigenin and synthetic stilbenes led to the discovery of 2,4,3",5"-tetramethoxystilbene, a selective inhibitor of P450 1B1 relative to other P450s.	2,4,3',5'-tetramethoxystilbene	83-113	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	140-148	
12628515-10	2003	2,4,3",5"-Tetramethoxystilbene also suppressed expression of P450 1B1 and growth of human mammary tumor cells.	2,4,3',5'-tetramethoxystilbene	0-30	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	61-69	
11754588-3	2002	Among the compounds tested, the most selective and potent CYP1B1 inhibitor was 2,3",4,5"-tetramethoxystilbene.	2,4,3',5'-tetramethoxystilbene	79-109	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	58-64	
22511118-3	2012	2,4,3",5"-Tetramethoxystilbene (TMS) is a potent and selective competitive inhibitor of CYP1B1 with an IC50 of 3 nM for EROD and ~90 nM for E2 4-hydroxylation.	2,4,3',5'-tetramethoxystilbene	0-30	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	88-94	
31783010-4	2020	Inhibition of CYP1B1 by TMS [(E)-2,3",4,5"-tetramethoxystilbene], the specific CYP1B1 inhibitor, remarkably enhanced the sensitivity of A549/Taxol to taxol.	2,4,3',5'-tetramethoxystilbene	29-63	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	14-20	
31783010-4	2020	Inhibition of CYP1B1 by TMS [(E)-2,3",4,5"-tetramethoxystilbene], the specific CYP1B1 inhibitor, remarkably enhanced the sensitivity of A549/Taxol to taxol.	2,4,3',5'-tetramethoxystilbene	29-63	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	79-85	
29232759-10	2018	Inhibition of CYP1B1 with the selective inhibitor 2,4,3",5"-tetramethoxystilbene (100 nM) partly reverses the effects of IFNgamma on epithelial permeability.	2,4,3',5'-tetramethoxystilbene	50-80	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	14-20	
28322972-4	2017	Many natural flavonoids and synthetic stilbenes show inhibitory activity toward CYP1B1 expression and function, notably isorhamnetin and 2,4,3",5"-tetramethoxystilbene.	2,4,3',5'-tetramethoxystilbene	137-167	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	80-86	
22511118-3	2012	2,4,3",5"-Tetramethoxystilbene (TMS) is a potent and selective competitive inhibitor of CYP1B1 with an IC50 of 3 nM for EROD and ~90 nM for E2 4-hydroxylation.	2,4,3',5'-tetramethoxystilbene	32-35	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	88-94	
16120791-0	2005	Modulation of human cytochrome P450 1B1 expression by 2,4,3",5"-tetramethoxystilbene.	2,4,3',5'-tetramethoxystilbene	54-84	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	20-39	
21669939-2	2011	We hypothesised that 2,3",4,5"-tetramethoxystilbene (TMS), an analogue of resveratrol and a potent CYP1B1 inhibitor, may inhibit r7, t8, t9-trihydroxy-c-10-(N(2)deoxyguanosyl)-7,8,9,10-tetrahydro-benzo[a]pyrene (BPdG) adduct formation in cells exposed to benzo[a]pyrene (BP).	2,4,3',5'-tetramethoxystilbene	21-51	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	99-105	
21669939-2	2011	We hypothesised that 2,3",4,5"-tetramethoxystilbene (TMS), an analogue of resveratrol and a potent CYP1B1 inhibitor, may inhibit r7, t8, t9-trihydroxy-c-10-(N(2)deoxyguanosyl)-7,8,9,10-tetrahydro-benzo[a]pyrene (BPdG) adduct formation in cells exposed to benzo[a]pyrene (BP).	2,4,3',5'-tetramethoxystilbene	53-56	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	99-105	
17295519-9	2007	The P450 1A1/1B1 inhibitor 2,4,3",5"-tetramethoxystilbene did not attenuate DNA adduct formation in the control H358 cells, suggesting that another P450 was responsible.	2,4,3',5'-tetramethoxystilbene	27-57	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	4-16	
16120791-1	2005	We have previously shown that 2,4,3",5"-tetramethoxystilbene (TMS), a synthetic trans-stilbene analog, is one of the most potently selective inhibitors of recombinant human cytochrome P450 1B1 (CYP1B1) in vitro.	2,4,3',5'-tetramethoxystilbene	30-60	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	173-192	
16120791-1	2005	We have previously shown that 2,4,3",5"-tetramethoxystilbene (TMS), a synthetic trans-stilbene analog, is one of the most potently selective inhibitors of recombinant human cytochrome P450 1B1 (CYP1B1) in vitro.	2,4,3',5'-tetramethoxystilbene	30-60	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	194-200	
16120791-1	2005	We have previously shown that 2,4,3",5"-tetramethoxystilbene (TMS), a synthetic trans-stilbene analog, is one of the most potently selective inhibitors of recombinant human cytochrome P450 1B1 (CYP1B1) in vitro.	2,4,3',5'-tetramethoxystilbene	62-65	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	173-192	
16120791-1	2005	We have previously shown that 2,4,3",5"-tetramethoxystilbene (TMS), a synthetic trans-stilbene analog, is one of the most potently selective inhibitors of recombinant human cytochrome P450 1B1 (CYP1B1) in vitro.	2,4,3',5'-tetramethoxystilbene	62-65	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	194-200	
15041469-6	2004	Antagonizing AhR activation and cytochrome P4501 activity with alpha-naphthoflavone, or inhibiting CYP1B1 activity with 2,4,3",5"-tetramethoxystilbene, however, prevented BaP-induced AR reduction.	2,4,3',5'-tetramethoxystilbene	120-150	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	99-105