PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30259565-6	2018	However, the increase in PI3K and P-AKT protein levels and the decrease in Bax, caspase-3, and caspase-9 protein levels induced by NaB treatment were reversed when the cells were pretreated with LY294002 (PI3K inhibitor).	nab	131-134	caspase 3	Homo sapiens	80-89	
29565269-6	2018	NaB (6.25 mM-50 mM) treatment inhibited cell viability by inducing apoptosis, which was evident with increased Annexin V-PE staining and caspase-3 activity.	nab	0-3	caspase 3	Homo sapiens	137-146	
22131152-8	2012	The apoptotic effects on BL cell lines of NaB/VP-16 and NaB/CDDP were followed by upregulation of Bim protein (P < 0.05), activation of caspase-3 and caspase-9, followed by Mcl-1 downregulation (P < 0.05).	nab	42-45	caspase 3	Homo sapiens	139-148	
23460921-5	2013	Nab-paclitaxel treatment increased expression of the mitotic-spindle associated phospho-stathmin irrespective of the baseline total or phosphorylated stathmin level, and induced mitotic cell death as confirmed through increased expression of cleaved-PARP and caspase-3.	nab	0-3	caspase 3	Homo sapiens	259-268	
35007916-16	2022	The protein levels of P53 and Caspase 3 increased with BA, NaB and SPT treatment for 72 h. CONCLUSIONS: BA, NaB and SPT show anti-cancer activity in the DMS-114 cell line without damaging MRC-5 cells, and some of the molecular mechanisms are involved in apoptosis and cell cycle arrest.	nab	59-62	caspase 3	Homo sapiens	30-39	
23251616-7	2012	In contrast, 10 mM NaB causes significant toxicity in preconfluent cells via apoptosis through caspase-3 activation with reduced GSTA1 activity.	nab	19-22	caspase 3	Homo sapiens	95-104	
18452462-9	2008	The Bcl-2 expression in bladder cancer cells is decreased and caspase-3 expression increased after NaB treatment.	nab	99-102	caspase 3	Homo sapiens	62-71	
34106394-9	2021	NaB notably ameliorated apoptotic regulatory proteins p-53, Caspase-3 and caspase-1 level, and reversed phosphorylation of extracellular signal-regulated kinases and p-38 proteins.	nab	0-3	caspase 3	Homo sapiens	60-69	
35007916-16	2022	The protein levels of P53 and Caspase 3 increased with BA, NaB and SPT treatment for 72 h. CONCLUSIONS: BA, NaB and SPT show anti-cancer activity in the DMS-114 cell line without damaging MRC-5 cells, and some of the molecular mechanisms are involved in apoptosis and cell cycle arrest.	nab	108-111	caspase 3	Homo sapiens	30-39	
31011879-7	2019	Western blotting results showed that combination of QCT and NaB increased apoptosis by decreasing anti-apoptotic Bcl-2 and increasing pro-apoptotic Bax, decreasing survivin, activating caspase-3, and degrading poly (ADP-ribose) polymerase (PARP).	nab	60-63	caspase 3	Homo sapiens	185-194