PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34066839-0	2021	Heme Oxygenase-1 Inhibition Potentiates the Effects of Nab-Paclitaxel-Gemcitabine and Modulates the Tumor Microenvironment in Pancreatic Ductal Adenocarcinoma.	nab	55-58	heme oxygenase 1	Mus musculus	0-16	
34066839-3	2021	We present evidence that nab-paclitaxel-gemcitabine (NPG) and/or a hypoxic tumor microenvironment (TME) up-regulate heme oxygenase-1 (HO-1), providing a survival advantage for tumors.	nab	25-28	heme oxygenase 1	Mus musculus	116-132	
34066839-3	2021	We present evidence that nab-paclitaxel-gemcitabine (NPG) and/or a hypoxic tumor microenvironment (TME) up-regulate heme oxygenase-1 (HO-1), providing a survival advantage for tumors.	nab	25-28	heme oxygenase 1	Mus musculus	134-138	
28684304-7	2017	Mechanistically, the NaB-mediated inhibition of Th17 cell differentiation may occur via inhibition of the nuclear factor erythroid 2-related factor 2 (Nrf2)/heme oxygenase 1 (HO-1)/interleukin-6 receptor pathway.	nab	21-24	heme oxygenase 1	Mus musculus	157-173	
31284554-5	2019	Besides, NAB upregulated the protein and mRNA expressions of heme oxygenase (HO)-1 when it exerted its anti-inflammatory effects.	nab	9-12	heme oxygenase 1	Mus musculus	61-82	
31284554-6	2019	Also, NAB restrained the production of NO by increasing HO-1 expression in LPS-stimulated RAW264.7 cells.	nab	6-9	heme oxygenase 1	Mus musculus	56-60	
31284554-7	2019	Thus, it is considered that the anti-inflammatory effect of NAB is associated with an induction of antioxidant protein HO-1, and thus NAB may be a potential HO-1 inducer for treating inflammatory diseases.	nab	60-63	heme oxygenase 1	Mus musculus	119-123	
31284554-7	2019	Thus, it is considered that the anti-inflammatory effect of NAB is associated with an induction of antioxidant protein HO-1, and thus NAB may be a potential HO-1 inducer for treating inflammatory diseases.	nab	134-137	heme oxygenase 1	Mus musculus	157-161	
28684304-7	2017	Mechanistically, the NaB-mediated inhibition of Th17 cell differentiation may occur via inhibition of the nuclear factor erythroid 2-related factor 2 (Nrf2)/heme oxygenase 1 (HO-1)/interleukin-6 receptor pathway.	nab	21-24	heme oxygenase 1	Mus musculus	175-179	
28684304-8	2017	Moreover, the NaB-mediated inhibition on Th17 cell differentiation and uveitis were abrogated when an HO-1 inhibitor, SnPP, was used.	nab	14-17	heme oxygenase 1	Mus musculus	102-106	
28684304-9	2017	These findings suggest that NaB inverts the differentiation of Th17 cells toward Treg cells and attenuates experimental autoimmune uveitis by modulating the Nrf2/HO-1 pathway.	nab	28-31	heme oxygenase 1	Mus musculus	162-166	
27799462-8	2017	NaB inhibited histone deacetylase (HDAC) activity and elevated the expression of Nrf2 and its downstream targets heme oxygenase 1 and NAD(P)H dehydrogenase quinone 1.	nab	0-3	heme oxygenase 1	Mus musculus	113-165