PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25261710-3 2014 In the present study, dipeptide prodrug approach was employed to circumvent efflux pumps (P-gp and MRP2) and CYP3A4 mediated metabolism of LPV. Dipeptides 22-31 ATP binding cassette subfamily C member 2 Canis lupus familiaris 99-103 18620036-0 2008 Interaction of dipeptide prodrugs of saquinavir with multidrug resistance protein-2 (MRP-2): evasion of MRP-2 mediated efflux. Dipeptides 15-24 ATP binding cassette subfamily C member 2 Canis lupus familiaris 53-83 18620036-0 2008 Interaction of dipeptide prodrugs of saquinavir with multidrug resistance protein-2 (MRP-2): evasion of MRP-2 mediated efflux. Dipeptides 15-24 ATP binding cassette subfamily C member 2 Canis lupus familiaris 85-90 18620036-0 2008 Interaction of dipeptide prodrugs of saquinavir with multidrug resistance protein-2 (MRP-2): evasion of MRP-2 mediated efflux. Dipeptides 15-24 ATP binding cassette subfamily C member 2 Canis lupus familiaris 104-109 18620036-3 2008 The objective of this study was to investigate whether derivatization of SQV to dipeptide prodrugs, valine-valine-saquinavir (Val-Val-SQV) and glycine-valine-saquinavir (Gly-Val-SQV), targeting peptide transporter can circumvent MRP-2 mediated efflux. Dipeptides 80-89 ATP binding cassette subfamily C member 2 Canis lupus familiaris 229-234