PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20159052-7 2010 In conclusion, these results indicate that AKF-PD inhibits the release of the proinflammatory cytokines (TNF-a and IL-1beta) and improves survival during lethal endotoxemia, which suggest this new pyridone agent can be a novel candidate for therapy of septic shock. Pyridones 197-205 tumor necrosis factor Mus musculus 105-110