PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24370012-1 2014 We discovered a series of novel and potent thiazolylpyridinone-based SCD1 inhibitors based on a 2-aminothiazole HTS hit by replacing the amide bond with a pyridinone moiety. Pyridones 52-62 stearoyl-Coenzyme A desaturase 1 Mus musculus 69-73