PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28076824-3 2017 The SAR revealed the minor influence of the amide group, importance of the pyridone ring both spatially around the pyridine ring and for possible pi-stacking, and confirmed a preference for inclusion of 3,4-dichlorobenzyl moieties, as bookends to the pyridone scaffold. Pyridones 75-83 sarcosine dehydrogenase Homo sapiens 4-7 23612851-4 2013 The preliminary SAR indicated that the conformationally restricted pyridones exhibited more potent cytotoxicity than the flexible counterparts. Pyridones 67-76 sarcosine dehydrogenase Homo sapiens 16-19