PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25811792-2 2015 Described here are the synthesis, biological evaluation, and pharmacokinetic evaluation of new synthetic small molecules based on pyridone-based HDAC inhibitors that specifically stabilize RUNX3 by acetylation and regulate its function. Pyridones 130-138 histone deacetylase 9 Homo sapiens 145-149