PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31211948-8	2019	Subsequently, we found that miR-221-3p could indirectly increase the expression of IFN-alpha (Interferon alpha) in astrocytes by targeting IRF2 (Interferon Regulatory Factor 2) and that miR-221-3p participated in the anti-neuroinflammatory signaling cascades induced by ketamine and paroxetine via the IRF2/IFN-alpha pathway.	Paroxetine	283-293	interferon alpha 1	Homo sapiens	83-92	
22353759-1	2012	In patients at high risk for recurrence of malignant melanoma, interferon-alpha (IFN-alpha), a stimulator of innate immunity, appears to induce distinct neurobehavioral symptom dimensions: a mood and anxiety syndrome, and a neurovegetative syndrome, of which the former is responsive to prophylactic administration of paroxetine.	Paroxetine	318-328	interferon alpha 1	Homo sapiens	81-90	
22353759-9	2012	Similar to patients with malignant melanoma receiving high-dose IFN-alpha, the depression symptom dimension is more responsive to paroxetine treatment in individuals undergoing concomitant IFN-alpha/ribavirin therapy.	Paroxetine	130-140	interferon alpha 1	Homo sapiens	64-73	
22353759-9	2012	Similar to patients with malignant melanoma receiving high-dose IFN-alpha, the depression symptom dimension is more responsive to paroxetine treatment in individuals undergoing concomitant IFN-alpha/ribavirin therapy.	Paroxetine	130-140	interferon alpha 1	Homo sapiens	189-198	
17292481-0	2007	A randomized trial of paroxetine to prevent interferon-alpha-induced depression in patients with hepatitis C. BACKGROUND: Interferon-alpha-(IFN-alpha) induced depression presents a challenge when treating patients with the hepatitis C virus (HCV).	Paroxetine	22-32	interferon alpha 1	Homo sapiens	140-149	
17292481-7	2007	However, in 10 of 11 patients who developed IFN-alpha-induced depression and entered the rescue arm of the study, open-label treatment with paroxetine helped reduce symptoms of depression.	Paroxetine	140-150	interferon alpha 1	Homo sapiens	44-53	
12975732-7	2003	Serotonin-reuptake-inhibitors including citalopram or paroxetine were shown to be effective for acute treatment of IFN-alpha associated depression.	Paroxetine	54-64	interferon alpha 1	Homo sapiens	115-124	
15107183-4	2004	Two of the five patients with baseline depression started an antidepressant treatment (paroxetine) together with the IFN-alpha and successfully completed the IFN-alpha therapy.	Paroxetine	87-97	interferon alpha 1	Homo sapiens	158-167	
11927189-1	2002	We have previously shown that the risk of major depression in patients with malignant melanoma undergoing interferon-alpha (IFN-alpha) therapy can be reduced by pretreatment with the antidepressant, paroxetine.	Paroxetine	199-209	interferon alpha 1	Homo sapiens	124-133