PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32741881-9 2020 CONCLUSIONS: The impaired systolic heart function of DCM mice was effectively improved by paroxetine therapy, partially through restoring the population of circulating Treg cells by targeting the GRK2-PI3K-Akt pathway. Paroxetine 90-100 thymoma viral proto-oncogene 1 Mus musculus 206-209 23275337-2 2013 Here, we demonstrate that incubation (2 h) of murine islets or Min6 beta cell line with the SSRIs paroxetine, fluoxetine, or sertraline inhibited insulin-induced Tyr phosphorylation of insulin receptor substrate (IRS)-2 protein and the activation of its downstream targets Akt and the ribosomal protein S6 kinase-1 (S6K1). Paroxetine 98-108 thymoma viral proto-oncogene 1 Mus musculus 273-276