PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14566199-4 2003 The role of paroxetine in clinically significant drug-drug interactions, especially involving metabolic inhibitory effects on the substrates of cytochrome p450 2D6, has long been suspected, but only isolated cases provide any evidence. Paroxetine 12-22 cytochrome P450 2D6 Homo sapiens 144-163 16542048-11 2006 Caution should also be exercised when prescribing strong cytochrome P450 2D6 inhibitors, such as paroxetine or fluoxetine, to women who are taking tamoxifen. Paroxetine 97-107 cytochrome P450 2D6 Homo sapiens 57-76 12404553-1 2001 Paroxetine inhibits cytochrome P(450) 2D6, which is involved in the metabolism of mirtazapine. Paroxetine 0-10 cytochrome P450 2D6 Homo sapiens 20-41 8861776-4 1996 For example, fluoxetine and paroxetine produce clinically significant inhibition of cytochrome P450 2D6 at their usually effective antidepressant dose, whereas citalopram, fluvoxamine or sertraline do not. Paroxetine 28-38 cytochrome P450 2D6 Homo sapiens 84-103