PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
6768169-0	1980	Induction of liver microsomal NADPH cytochrome C reductase and cytochrome P-450 by some new synthetic pyrethroids.	Pyrethrins	102-113	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	63-79	
29779438-1	2019	The metabolism of the pyrethroids deltamethrin (DLM), cis-permethrin (CPM) and trans-permethrin (TPM) was studied in human expressed cytochrome P450 (CYP) and carboxylesterase (CES) enzymes.	Pyrethrins	22-33	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	150-153	
32672501-2	2020	Pyrethroid metabolism was also studied with some human expressed cytochrome P450 (CYP) and carboxylesterase (CES) enzymes.	Pyrethrins	0-10	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	65-80	
32672501-2	2020	Pyrethroid metabolism was also studied with some human expressed cytochrome P450 (CYP) and carboxylesterase (CES) enzymes.	Pyrethrins	0-10	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	82-85	
32672501-10	2020	All pyrethroids were metabolised by some of the human expressed CYP enzymes studied and apart from BIF were also metabolised by CES enzymes.	Pyrethrins	4-15	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	64-67	
29779438-3	2019	Other CYP enzymes contributing to the metabolism of one or more of the three pyrethroids were CYP1A2, CYP2C8, CYP2C9*1, CYP2D6*1, CYP3A4 and CYP3A5.	Pyrethrins	77-88	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	6-9	
29779438-6	2019	Apparent CLint values for pyrethroid metabolism by CYP and CES enzymes were scaled to per gram of adult human liver using abundance values for microsomal CYP enzymes and for CES enzymes in liver microsomes and cytosol.	Pyrethrins	26-36	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	51-54	
29779438-8	2019	Due to their higher abundance, all three pyrethroids were extensively metabolised by CES enzymes in adult human liver, with CYP enzymes only accounting for 2%, 10% and 1% of total metabolism for DLM, CPM and TPM, respectively.	Pyrethrins	41-52	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	124-127