PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33706615-0 2021 Synthetic pyrethroids common metabolite 3-phenoxybenzoic acid induces caspase-3 and Bcl-2 mediated apoptosis in human hepatocyte cells. Pyrethrins 10-21 caspase 3 Homo sapiens 70-79 27939866-5 2017 In addition, the current data indicate that natural pyrethrins cause a reduction in the mitochondrial membrane potential (Deltapsim), increase reactive oxygen species production, and up-regulate the Bax/Bcl-2 expression, leading to the release of cytochrome-c into the cytosol, activation of caspase-9 and caspase-3 and cleavage of poly (ADP-ribose) polymerase (PARP). Pyrethrins 52-62 caspase 3 Homo sapiens 306-315