PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11164833-3 2001 injection of racemic-flurbiprofen (0.3, 3 and 9 mg/kg) has weaker effects on carrageenan-evoked spinal c-Fos protein expression and peripheral edema than those previously described in the same inflammatory nociceptive model in awake rats. Flurbiprofen 21-33 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 103-108 9776348-7 1998 Intravenous racemic-flurbiprofen (0.3, 3 and 9 mg kg(-1)) dose-relatedly reduced the carrageenan-evoked oedema and spinal c-Fos expression (r=0.64, r=0.88 and r=0.84 for paw diameter, ankle diameter and number of c-Fos-LI neurons; P<0.05. Flurbiprofen 20-32 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 122-127 11011034-0 2000 Effects of flurbiprofen and its enantiomers on the spinal c-Fos protein expression induced by noxious heat stimuli in the anaesthetized rat. Flurbiprofen 11-23 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 58-63 11011034-4 2000 The same doses of R(-)-flurbiprofen produced dose-related effects (r=0.58, P<0.05) with weak, but significant, effects for doses of 3 and 9 mg/kg (18+/-6% and 26+/-5% reduction of the number of noxious heat-evoked c-Fos-IR nuclei in laminae I-II, P<0.05 and P<0.01, respectively). Flurbiprofen 18-35 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 217-222 9776348-7 1998 Intravenous racemic-flurbiprofen (0.3, 3 and 9 mg kg(-1)) dose-relatedly reduced the carrageenan-evoked oedema and spinal c-Fos expression (r=0.64, r=0.88 and r=0.84 for paw diameter, ankle diameter and number of c-Fos-LI neurons; P<0.05. Flurbiprofen 20-32 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 213-218 9776348-10 1998 Similar effects to those of intravenous racemic-flurbiprofen were obtained with intravenous S(+)-flurbiprofen (0.3, 3 and 9 mg kg(-1)) which dose-relatedly reduced the number of c-Fos-LI neurons (r=0.69, P<0.01) and diameters of paw and ankle (r=0.56 and r=0.52 respectively, P<0.05 for both). Flurbiprofen 92-109 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 178-183 9776348-16 1998 Intraplantar racemic-flurbiprofen (1, 10 and 30 microg) dose-relatedly reduced the carrageenan-enhanced ankle diameter (r=0.81, P<0.001) and the number of c-Fos-LI neurons in L4-L5 segments (r=0.83, P<0.001). Flurbiprofen 21-33 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 158-163 9776348-19 1998 For intraplantar S(+)-flurbiprofen (1, 10 and 30 microg) the dose-related effects (r=0.77, r=0.60 and r=0.59 for c-Fos-LI neurons, paw and ankle diameters respectively, P<0.001, P<0.01 and P<0.01) were similar to those of racemic-flurbiprofen. Flurbiprofen 18-34 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 113-118 9776348-19 1998 For intraplantar S(+)-flurbiprofen (1, 10 and 30 microg) the dose-related effects (r=0.77, r=0.60 and r=0.59 for c-Fos-LI neurons, paw and ankle diameters respectively, P<0.001, P<0.01 and P<0.01) were similar to those of racemic-flurbiprofen. Flurbiprofen 22-34 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 113-118