PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32312970-6 2020 Furthermore, Drp1 mediated metabolic disorders and inhibited the levels of mitochondrial glutathione to impair free radical scavenging, leading to further increases in ROS and the exacerbation of mitochondrial dysfunction after ischemic injury. ros 168-171 dynamin 1 like Homo sapiens 13-17 32184231-5 2020 By live-imaging, we found that loss of function of the mitochondrial fission protein Dynamin-related protein 1 (Drp1) compromises the increase of cytosolic and mitochondrial calcium upon wounding and leads to reduced ROS production and F-actin defects at the wound edge, culminating in wound healing impairment. ros 217-220 dynamin 1 like Homo sapiens 85-110 32184231-5 2020 By live-imaging, we found that loss of function of the mitochondrial fission protein Dynamin-related protein 1 (Drp1) compromises the increase of cytosolic and mitochondrial calcium upon wounding and leads to reduced ROS production and F-actin defects at the wound edge, culminating in wound healing impairment. ros 217-220 dynamin 1 like Homo sapiens 112-116 34462274-5 2022 Mechanistically, dynamin-related protein 1 (DRP1)-dependent excessive mitochondrial fragmentation in HSC/Ps led to excessive ROS production, induced inflammatory signaling activation, and promoted subsequent dysplasia formation and impairment of granulopoiesis. ros 125-128 dynamin 1 like Homo sapiens 17-42 34462274-5 2022 Mechanistically, dynamin-related protein 1 (DRP1)-dependent excessive mitochondrial fragmentation in HSC/Ps led to excessive ROS production, induced inflammatory signaling activation, and promoted subsequent dysplasia formation and impairment of granulopoiesis. ros 125-128 dynamin 1 like Homo sapiens 44-48 34203664-9 2021 Here, we show that Flt3-ITD+ cells are sensitive to an IB-induced dynamin 1-like (Drp1)-p38-ROS pathway. ros 92-95 dynamin 1 like Homo sapiens 82-86 32696439-4 2020 Dynamin-related protein 1 (Drp1)-mediated mitochondrial fragmentation leads to excess ROS generation, which is implicated in the pathogenesis of neuropathic pain. ros 86-89 dynamin 1 like Homo sapiens 0-25 32696439-4 2020 Dynamin-related protein 1 (Drp1)-mediated mitochondrial fragmentation leads to excess ROS generation, which is implicated in the pathogenesis of neuropathic pain. ros 86-89 dynamin 1 like Homo sapiens 27-31 32696439-8 2020 We summarized a Drp1-mitochondrial fission-ROS cycle that potentially functions in neuropathic pain and is regulated by posttranslational modifications and Ca2+. ros 43-46 dynamin 1 like Homo sapiens 16-20 29360568-11 2018 Pharmacological or genetic inhibition of DRP1 enhanced palmitate-induced mitochondrial ROS production, c-Jun phosphorylation, and inflammatory cytokine expression. ros 87-90 dynamin 1 like Homo sapiens 41-45 27027430-0 2016 Differentiation inducing factor 3 mediates its anti-leukemic effect through ROS-dependent DRP1-mediated mitochondrial fission and induction of caspase-independent cell death. ros 76-79 dynamin 1 like Homo sapiens 90-94 25857570-10 2015 In addition, Overexpression of DRP1 promoted the activation of p38, the accumulation of ROS, mitochondrial dysfunction, and the synthesis of collagen IV, and all these changes are suppressed by Midivi-1. ros 88-91 dynamin 1 like Homo sapiens 31-35