PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26990437-2	2017	Utilizing a mouse model, null for Cyp1b1 and expressing human CYP1B1, we tested the hypothesis that hCYP1B1 is important for dibenzo[def,p]chrysene (DBC) transplacental carcinogenesis.	dibenzo(a,l)pyrene	125-147	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	100-107	
26990437-2	2017	Utilizing a mouse model, null for Cyp1b1 and expressing human CYP1B1, we tested the hypothesis that hCYP1B1 is important for dibenzo[def,p]chrysene (DBC) transplacental carcinogenesis.	dibenzo(a,l)pyrene	149-152	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	100-107	
17509623-0	2007	Cytotoxicity and mutagenicity of dibenzo[a,l]pyrene and (+/-)-dibenzo[a,l]pyrene-11,12-dihydrodiol in V79MZ cells co-expressing either hCYP1A1 or hCYP1B1 together with human glutathione-S-transferase A1.	dibenzo(a,l)pyrene	33-51	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	146-153	
17623886-0	2007	Inhibition of human cytochrome p450 1b1 further clarifies its role in the activation of dibenzo[a,l]pyrene in cells in culture.	dibenzo(a,l)pyrene	88-106	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	20-39	
16581046-4	2006	The total turnover of CYP-mediated transformation of DB[a,l]P was as follows: human CYP1B1>fish CYP1A1 approximately human CYP1A1>>rat CYP1A2>rat CYP1A1.	dibenzo(a,l)pyrene	53-61	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	84-90	
16581046-8	2006	DB[a,l]P-dependent cytotoxicities (EC(50)) were found in the following order: human CYP1A1 (12 nM)>fish CYP1A1 (30 nM)>human CYP1B1 (45 nM)>>other forms.	dibenzo(a,l)pyrene	0-8	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	131-137	
10207125-0	1999	Metabolic activation of dibenzo[a,l]pyrene by human cytochrome P450 1A1 and P450 1B1 expressed in V79 Chinese hamster cells.	dibenzo(a,l)pyrene	24-42	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	76-84	
10207125-1	1999	Metabolic activation of the strongly carcinogenic polycyclic aromatic hydrocarbon (PAH) dibenzo[a,l]pyrene (DB[a,l]P) and its trans-8,9-dihydrodiol (trans-8,9-diol) catalyzed by human cytochromes P450 (P450) 1A1 and 1B1 was investigated.	dibenzo(a,l)pyrene	108-116	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	184-219	
9625737-0	1998	Stable expression of human cytochrome P450 1B1 in V79 Chinese hamster cells and metabolically catalyzed DNA adduct formation of dibenzo[a,l]pyrene.	dibenzo(a,l)pyrene	128-146	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	27-46	
9625737-14	1998	These results indicate that human P450 1B1 and P450 1A1 differ in their regio- and stereochemical selectivity of activation of DB[a,l]P with P450 1B1 forming a higher proportion of the highly carcinogenic (-)-anti-(11R, 12S,13S,14R)-DB[a,l]PDE metabolite.	dibenzo(a,l)pyrene	127-135	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	34-55	
9625737-14	1998	These results indicate that human P450 1B1 and P450 1A1 differ in their regio- and stereochemical selectivity of activation of DB[a,l]P with P450 1B1 forming a higher proportion of the highly carcinogenic (-)-anti-(11R, 12S,13S,14R)-DB[a,l]PDE metabolite.	dibenzo(a,l)pyrene	127-135	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	34-42