PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18997418-2	2008	Co-treatment with EGCG potentiated the cytotoxicity induced by benzyl isothiocyanate (BITC) and H(2)O(2), both being inhibited by ERK and JNK inhibitors.	benzyl isothiocyanate	63-84	mitogen-activated protein kinase 8	Homo sapiens	138-141	
19549704-2	2009	In the present study, we demonstrate the activation of all the three (MAPK) family members [extracellular signal-regulated protein kinase (ERK), c-jun N-terminal kinase (JNK) and P38] in response to BITC treatment.	benzyl isothiocyanate	199-203	mitogen-activated protein kinase 8	Homo sapiens	145-168	
19549704-2	2009	In the present study, we demonstrate the activation of all the three (MAPK) family members [extracellular signal-regulated protein kinase (ERK), c-jun N-terminal kinase (JNK) and P38] in response to BITC treatment.	benzyl isothiocyanate	199-203	mitogen-activated protein kinase 8	Homo sapiens	170-173	
19549704-7	2009	Significant protection from BITC-induced G(2)/M arrest was observed in the cells pre-treated with MAPK kinase (MEK-1) but not JNK or P38 inhibitors.	benzyl isothiocyanate	28-32	mitogen-activated protein kinase 8	Homo sapiens	126-129	
19549704-8	2009	On the other hand, BITC-induced apoptosis was almost completely abrogated in the cells pre-treated with MEK-1, JNK or P38 inhibitors.	benzyl isothiocyanate	19-23	mitogen-activated protein kinase 8	Homo sapiens	111-114	
19549704-9	2009	Similarly, MAPK8-shRNA also offered almost complete protection against BITC-induced G(2)/M arrest and apoptosis.	benzyl isothiocyanate	71-75	mitogen-activated protein kinase 8	Homo sapiens	11-16	
19549704-13	2009	Taken together, our results suggest that BITC-mediated G(2)/M arrest is mediated through ERK activation, whereas apoptosis is via ERK, JNK and P38.	benzyl isothiocyanate	41-45	mitogen-activated protein kinase 8	Homo sapiens	135-138	
18997418-2	2008	Co-treatment with EGCG potentiated the cytotoxicity induced by benzyl isothiocyanate (BITC) and H(2)O(2), both being inhibited by ERK and JNK inhibitors.	benzyl isothiocyanate	86-90	mitogen-activated protein kinase 8	Homo sapiens	138-141	
18768478-8	2008	Pharmacological inhibition of both JNK and p38 MAPK conferred partial yet significant protection against BITC-induced apoptosis.	benzyl isothiocyanate	105-109	mitogen-activated protein kinase 8	Homo sapiens	35-38	
10092525-0	1999	Temporal effects of the detoxification enzyme inducer, benzyl isothiocyanate: activation of c-Jun N-terminal kinase prior to the transcription factors AP-1 and NFkappaB.	benzyl isothiocyanate	55-76	mitogen-activated protein kinase 8	Homo sapiens	92-115