PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28969043-8 2017 Isothiocyanates-mediated inhibition of FAK phosphorylation suppressed phosphorylation of ERK1/2 and Akt in U2OS and A549 cells, along with the translocation of p65 and c-Fos, suggesting that isothiocyanates inhibit MMP-9 expression and cell invasion by blocking phosphorylation of FAK. Isothiocyanates 0-15 AKT serine/threonine kinase 1 Homo sapiens 100-103 28969043-10 2017 Thus, isothiocyanates act as anti-metastatic compounds that suppress MMP-9 activity/expression by inhibiting NF-kappaB and AP-1 via suppression of the FAK/ERK and FAK/Akt signaling pathways. Isothiocyanates 6-21 AKT serine/threonine kinase 1 Homo sapiens 167-170