PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9458080-1 1998 Isothiocyanates exert strong anticarcinogenic effects in a number of animal models of cancer, presumably by modulation of xenobiotic-metabolizing enzymes, such as by inhibition of cytochrome P-450 and/or by induction of phase II detoxifying enzymes. Isothiocyanates 0-15 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 180-196 11506821-6 2001 Earlier in vivo experiments with rodents indicated that indoles and isothiocyanates, two major groups of glucosinolate breakdown products, attenuate the effects of polycyclic aromatic hydrocarbons (PAHs) and nitrosamines via induction of GST and inhibition of cytochrome-P450 isoenzymes, respectively. Isothiocyanates 68-83 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 260-275