PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31541852-5 2019 Presence of GMG-ITC prior to development of oxidative stress condition, downregulated the expression of cyt-c, p53, Apaf-1, Bax, CASP3, CASP8 and CASP9 genes with concurrent upregulation of Bcl-2 gene in mitochondrial apoptotic signalling pathway. Isothiocyanates 12-19 caspase 3 Homo sapiens 129-134 9458080-0 1998 Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity. Isothiocyanates 16-31 caspase 3 Homo sapiens 53-62 9458080-3 1998 Treatment with apoptosis-inducing concentrations of isothiocyanates also caused rapid and transient induction of caspase-3/CPP32-like activity. Isothiocyanates 52-67 caspase 3 Homo sapiens 113-122 9458080-3 1998 Treatment with apoptosis-inducing concentrations of isothiocyanates also caused rapid and transient induction of caspase-3/CPP32-like activity. Isothiocyanates 52-67 caspase 3 Homo sapiens 123-128 9458080-6 1998 These results suggest that isothiocyanates may induce apoptosis through a caspase-3-dependent mechanism. Isothiocyanates 27-42 caspase 3 Homo sapiens 74-83