PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26134366-0 2015 Sensitization of HER2 Positive Breast Cancer Cells to Lapatinib Using Plants-Derived Isothiocyanates. Isothiocyanates 85-100 erb-b2 receptor tyrosine kinase 2 Homo sapiens 17-21 27154770-0 2017 Combination of lapatinib with isothiocyanates overcomes drug resistance and inhibits migration of HER2 positive breast cancer cells. Isothiocyanates 30-45 erb-b2 receptor tyrosine kinase 2 Homo sapiens 98-102 27154770-3 2017 The aim of this study was to verify whether combinations of lapatinib with one of isothiocyanates (sulforaphane, erucin or sulforaphene), targeting different levels of HER2 signaling pathway, exert stronger cytotoxic effect than therapy targeting the receptor only, using heterogeneous populations consisting of lapatinib-sensitive and lapatinib-resistant breast cancer cells. Isothiocyanates 82-97 erb-b2 receptor tyrosine kinase 2 Homo sapiens 168-172