PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25550793-6 2014 Using soft agar assay to detecting the influence of miR-29 on the increased colony formation caused by TGF-beta1 on the human orbital fibroblasts. Agar 11-15 transforming growth factor beta 1 Homo sapiens 103-112 23467611-5 2013 Stable reexpression of Arkadia in lung carcinoma NCI-H460 cells, which we show contain a hemizygous nonsense mutation in the Arkadia/RNF111 gene, efficiently restored TGF-beta-induced Smad3-dependent transcription, and substantially decreased the ability of these cells to grow in soft agar in vitro. Agar 286-290 transforming growth factor beta 1 Homo sapiens 167-175 7669137-11 1995 TGF-beta caused dose-dependent stimulations of total protein as well as glycosaminoglycan synthesis in chondrocytes cultured in monolayer and agar. Agar 142-146 transforming growth factor beta 1 Homo sapiens 0-8 21613822-4 2011 We show here that TGF-beta stimulates growth of human and murine pancreatic cancer cell lines (PCCs) when embedded in a 3% collagen IV/laminin-rich gelatinous medium (Matrigel ) over a solidified layer of soft agar. Agar 210-214 transforming growth factor beta 1 Homo sapiens 18-26 7669137-12 1995 The stimulating effect of TGF-beta on matrix synthesis was greater for chondrocytes cultured in agar than for chondrocytes cultured in monolayer. Agar 96-100 transforming growth factor beta 1 Homo sapiens 26-34 1969420-5 1990 The ligand-activated cells became morphologically transformed and grew in agar in the presence of EGF and TGF beta as efficiently as did the ligand-independent neu oncogene-transformed cells. Agar 74-78 transforming growth factor beta 1 Homo sapiens 106-114 7647036-6 1995 E1A also interferes with growth stimulation of NRK cells by TGF beta 1, both in monolayer and in soft agar. Agar 102-106 transforming growth factor beta 1 Homo sapiens 60-70 8385096-12 1993 Transforming growth factor beta inhibits DiFi cell growth in soft agar and suppresses c-myc expression in these cells. Agar 66-70 transforming growth factor beta 1 Homo sapiens 0-31 1933858-9 1991 In addition, these clones respond far more strongly to TGF-beta 1 than do the parental Cl 41 cells in terms of both the numbers and the sizes of colonies formed in soft agar. Agar 169-173 transforming growth factor beta 1 Homo sapiens 55-65 1999144-5 1991 Human TGF-beta over the dose range of 2.5-80 pM significantly stimulated or inhibited soft-agar colony formation of either NRK 49F or A549 cells, respectively, and caused a severalfold increase in biosynthetically labeled [35S]fibronectin in NRK 49F and ROS 17/2.8 cells. Agar 91-95 transforming growth factor beta 1 Homo sapiens 6-14 1996655-10 1991 This was not due to the presence of TGF-beta inhibitors in fibroblast culture media, because the addition of purified porcine TGF-beta to conditioned medium from human lung fibroblast cultures yielded the expected increase in NRK cell growth in soft agar. Agar 250-254 transforming growth factor beta 1 Homo sapiens 126-134 2930547-5 1989 Furthermore, TGF-beta decreased the concentrations of FGF needed for the induction of cell growth in soft agar by 40- to 100-fold. Agar 106-110 transforming growth factor beta 1 Homo sapiens 13-21 2541895-7 1989 Levels of TGF-beta-like material in the colon carcinoma populations were comparable (HT-29) or elevated (DLD-1, SW620) only 3- to 4-fold (soft agar) or 1- to 3-fold (radioreceptor binding) compared to IEC cells or NRK-52E. Agar 143-147 transforming growth factor beta 1 Homo sapiens 10-18 2337474-4 1990 However, the combination of TGF-beta and RA resulted an increase in RA inhibitory effect on MCF-7 monolayer growth and a 80% reduction in colony formation in soft agar. Agar 163-167 transforming growth factor beta 1 Homo sapiens 28-36 2840442-5 1988 Contrarily, porcine TGF-beta decreases the A I cloning efficiency of Ki-49F cells in agar-gelled medium; this effect is only partly reversed by EGF, which does not synergise with TGF-beta to enhance the A I growth as in the case of untransformed 49F cells. Agar 85-89 transforming growth factor beta 1 Homo sapiens 20-28 3491081-3 1986 Treatment of the cells with TGF beta caused a significant decrease in the PA activity of the culture medium as analyzed by the caseinolysis-in-agar assays. Agar 143-147 transforming growth factor beta 1 Homo sapiens 28-36 6602340-6 1983 The purified placental TGF-beta caused half-maximal growth stimulation of indicator cells in soft agar at 64-72 pg/ml (3 pM) in the presence of EGF at 2 ng/ml (0.34 nM). Agar 98-102 transforming growth factor beta 1 Homo sapiens 23-31