PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25550793-6	2014	Using soft agar assay to detecting the influence of miR-29 on the increased colony formation caused by TGF-beta1 on the human orbital fibroblasts.	Agar	11-15	transforming growth factor beta 1	Homo sapiens	103-112	
6602340-6	1983	The purified placental TGF-beta caused half-maximal growth stimulation of indicator cells in soft agar at 64-72 pg/ml (3 pM) in the presence of EGF at 2 ng/ml (0.34 nM).	Agar	98-102	transforming growth factor beta 1	Homo sapiens	23-31	
23467611-5	2013	Stable reexpression of Arkadia in lung carcinoma NCI-H460 cells, which we show contain a hemizygous nonsense mutation in the Arkadia/RNF111 gene, efficiently restored TGF-beta-induced Smad3-dependent transcription, and substantially decreased the ability of these cells to grow in soft agar in vitro.	Agar	286-290	transforming growth factor beta 1	Homo sapiens	167-175	
21613822-4	2011	We show here that TGF-beta stimulates growth of human and murine pancreatic cancer cell lines (PCCs) when embedded in a 3% collagen IV/laminin-rich gelatinous medium (Matrigel ) over a solidified layer of soft agar.	Agar	210-214	transforming growth factor beta 1	Homo sapiens	18-26	
7647036-6	1995	E1A also interferes with growth stimulation of NRK cells by TGF beta 1, both in monolayer and in soft agar.	Agar	102-106	transforming growth factor beta 1	Homo sapiens	60-70	
8385096-12	1993	Transforming growth factor beta inhibits DiFi cell growth in soft agar and suppresses c-myc expression in these cells.	Agar	66-70	transforming growth factor beta 1	Homo sapiens	0-31	
1999144-5	1991	Human TGF-beta over the dose range of 2.5-80 pM significantly stimulated or inhibited soft-agar colony formation of either NRK 49F or A549 cells, respectively, and caused a severalfold increase in biosynthetically labeled [35S]fibronectin in NRK 49F and ROS 17/2.8 cells.	Agar	91-95	transforming growth factor beta 1	Homo sapiens	6-14	
1996655-10	1991	This was not due to the presence of TGF-beta inhibitors in fibroblast culture media, because the addition of purified porcine TGF-beta to conditioned medium from human lung fibroblast cultures yielded the expected increase in NRK cell growth in soft agar.	Agar	250-254	transforming growth factor beta 1	Homo sapiens	126-134	
1969420-5	1990	The ligand-activated cells became morphologically transformed and grew in agar in the presence of EGF and TGF beta as efficiently as did the ligand-independent neu oncogene-transformed cells.	Agar	74-78	transforming growth factor beta 1	Homo sapiens	106-114	
2541895-7	1989	Levels of TGF-beta-like material in the colon carcinoma populations were comparable (HT-29) or elevated (DLD-1, SW620) only 3- to 4-fold (soft agar) or 1- to 3-fold (radioreceptor binding) compared to IEC cells or NRK-52E.	Agar	143-147	transforming growth factor beta 1	Homo sapiens	10-18	
3491081-3	1986	Treatment of the cells with TGF beta caused a significant decrease in the PA activity of the culture medium as analyzed by the caseinolysis-in-agar assays.	Agar	143-147	transforming growth factor beta 1	Homo sapiens	28-36	
7669137-11	1995	TGF-beta caused dose-dependent stimulations of total protein as well as glycosaminoglycan synthesis in chondrocytes cultured in monolayer and agar.	Agar	142-146	transforming growth factor beta 1	Homo sapiens	0-8	
7669137-12	1995	The stimulating effect of TGF-beta on matrix synthesis was greater for chondrocytes cultured in agar than for chondrocytes cultured in monolayer.	Agar	96-100	transforming growth factor beta 1	Homo sapiens	26-34	
1933858-9	1991	In addition, these clones respond far more strongly to TGF-beta 1 than do the parental Cl 41 cells in terms of both the numbers and the sizes of colonies formed in soft agar.	Agar	169-173	transforming growth factor beta 1	Homo sapiens	55-65	
2337474-4	1990	However, the combination of TGF-beta and RA resulted an increase in RA inhibitory effect on MCF-7 monolayer growth and a 80% reduction in colony formation in soft agar.	Agar	163-167	transforming growth factor beta 1	Homo sapiens	28-36	
2930547-5	1989	Furthermore, TGF-beta decreased the concentrations of FGF needed for the induction of cell growth in soft agar by 40- to 100-fold.	Agar	106-110	transforming growth factor beta 1	Homo sapiens	13-21	
2840442-5	1988	Contrarily, porcine TGF-beta decreases the A I cloning efficiency of Ki-49F cells in agar-gelled medium; this effect is only partly reversed by EGF, which does not synergise with TGF-beta to enhance the A I growth as in the case of untransformed 49F cells.	Agar	85-89	transforming growth factor beta 1	Homo sapiens	20-28