PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1981145-10 1990 TGF alpha-infected MCF-10A cells secrete 15- to 20-fold more TGF alpha protein than MCF-10A cells, form colonies in soft agar, exhibit an enhanced growth rate in serum-free medium, and show a decreased mitogenic response to exogenous EGF or TGF alpha at a level equivalent to Ha-ras-transformed MCF-10A cells. Agar 121-125 transforming growth factor alpha Homo sapiens 0-9 1567383-4 1992 An analysis of biological activity using as assays radioreceptor binding competition and colony formation in soft agar showed that the following mutations destroy the activity of TGF-alpha: Gly-19 to Val, Val-33 to Pro and Gly-40 to Val. Agar 114-118 transforming growth factor alpha Homo sapiens 179-188 1813068-8 1991 We conclude that IGFs and TGF-alpha are important mediators of E2-stimulated MCF-7 cell growth in soft agar. Agar 103-107 transforming growth factor alpha Homo sapiens 26-35 1981145-11 1990 Growth of TGF alpha-infected MCF-10A cells in soft agar is completely inhibited by anti-TGF alpha neutralizing or anti-EGF receptor blocking monoclonal antibodies. Agar 51-55 transforming growth factor alpha Homo sapiens 10-19 1981145-11 1990 Growth of TGF alpha-infected MCF-10A cells in soft agar is completely inhibited by anti-TGF alpha neutralizing or anti-EGF receptor blocking monoclonal antibodies. Agar 51-55 transforming growth factor alpha Homo sapiens 88-97 2320376-6 1990 The addition of TGF-alpha or EGF (epidermal growth factor) protein to RA-untreated NT2/D1 cells augments soft agar cloning under limited fetal calf serum conditions. Agar 110-114 transforming growth factor alpha Homo sapiens 16-25 2786419-5 1989 A neutralizing mouse monoclonal antibody generated against the low molecular weight human TGF alpha peptide was able to inhibit colony formation in soft agar by TGF alpha-transfected NOG-8 clones that produced high levels by TGF alpha. Agar 153-157 transforming growth factor alpha Homo sapiens 90-99 2786419-5 1989 A neutralizing mouse monoclonal antibody generated against the low molecular weight human TGF alpha peptide was able to inhibit colony formation in soft agar by TGF alpha-transfected NOG-8 clones that produced high levels by TGF alpha. Agar 153-157 transforming growth factor alpha Homo sapiens 161-170 2786419-5 1989 A neutralizing mouse monoclonal antibody generated against the low molecular weight human TGF alpha peptide was able to inhibit colony formation in soft agar by TGF alpha-transfected NOG-8 clones that produced high levels by TGF alpha. Agar 153-157 transforming growth factor alpha Homo sapiens 161-170