platelet activating factor receptor ; Homo sapiens






158 Article(s)
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1 1656963 Characterization of a human cDNA that encodes a functional receptor for platelet activating factor. Biochem Biophys Res Commun 1991 Oct 15 1
2 2154211 Evidence for a platelet-activating factor receptor on human lymphoblastoid B cells: activation of the phosphatidylinositol cycle and induction of calcium mobilization. Biochem Biophys Res Commun 1990 Jan 30 2
3 2154654 Binding of radiolabeled antagonist to platelet-activating-factor receptor in human lung membranes: shifting of agonist binding affinity states by cations and guanine nucleotide. Life Sci 1990 4
4 3026378 GTP regulation of platelet-activating factor binding to human neutrophil membranes. Biochem Biophys Res Commun 1986 Nov 26 1
5 3183958 Biological effects of the orally active platelet activating factor receptor antagonist SDZ 64-412. J Pharmacol Exp Ther 1988 Nov 1
6 7490477 Identification of functional platelet-activating factor receptors on human keratinocytes. J Invest Dermatol 1995 Dec 3
7 7514637 Zymosan-induced IL-8 release from human neutrophils involves activation via the CD11b/CD18 receptor and endogenous platelet-activating factor as an autocrine modulator. J Immunol 1994 Jun 1 1
8 7539741 Amelioration of bleomycin-induced lung fibrosis by treatment with the platelet activating factor receptor antagonist WEB 2086 in hamsters. Exp Lung Res 1995 Mar-Apr 3
9 7559653 The role of N-glycosylation for functional expression of the human platelet-activating factor receptor. Glycosylation is required for efficient membrane trafficking. J Biol Chem 1995 Oct 20 2
10 7756000 Findings of automatic border detection in subjects with left ventricular diastolic dysfunction by Doppler echocardiography. J Am Soc Echocardiogr 1995 Mar-Apr 4
11 7802642 Platelet-activating factor (PAF) positively auto-regulates the expression of human PAF receptor transcript 1 (leukocyte-type) through NF-kappa B. Biochem Biophys Res Commun 1994 Dec 15 2
12 7830265 Antitumor activity of 5-aryl-2,3-dihydroimidazo[2,1-a]isoquinolines. J Med Chem 1995 Jan 20 1
13 7848283 Expression of human platelet-activating factor receptor gene in EoL-1 cells following butyrate-induced differentiation. Biochem J 1995 Feb 1 1
14 7900545 Functional PAF receptors in glia cells: binding parameters and regulation of expression. Int J Dev Neurosci 1994 Nov 2
15 7910528 Intracellular oxidative stress induced by nitric oxide synthesis inhibition increases endothelial cell adhesion to neutrophils. Circ Res 1994 Jun 1
16 7932382 Functional platelet-activating factor receptors linked to inositol lipid hydrolysis, calcium mobilization and tyrosine kinase activity in the human endometrial HEC-1B cell line. J Reprod Fertil 1994 Jul 2
17 7956274 Platelet-activating factor receptor antagonist BN 52021 in the treatment of severe sepsis: a randomized, double-blind, placebo-controlled, multicenter clinical trial. BN 52021 Sepsis Study Group. Crit Care Med 1994 Nov 1
18 7967680 Platelet-activating factor plays an important role in reperfusion injury in myocardium. Efficacy of platelet-activating factor receptor antagonist (CV-3988) as compared with leukocyte-depleted reperfusion. J Thorac Cardiovasc Surg 1994 Nov 1
19 8176225 IFN-gamma up-regulates platelet-activating factor receptor gene expression in human monocytes. J Immunol 1994 May 15 2
20 8179916 Expression of platelet-activating factor receptor mRNA in human and guinea pig lung. Am J Respir Cell Mol Biol 1994 May 1
21 8203898 Biochemical characterization of the interaction of lipid phosphoric acids with human platelets: comparison with platelet activating factor. Arch Biochem Biophys 1994 Jun 1
22 8207248 Functional platelet-activating factor receptors are expressed by monocytes and granulocytes but not by resting or activated T and B lymphocytes from normal individuals or patients with asthma. J Immunol 1994 Jul 1 1
23 8283038 Autocrine stimulation of B lymphocytes by a platelet-activating factor receptor agonist, 1-palmitoyl-2-acetyl-sn-glycero-3-phosphocholine. J Immunol 1994 Jan 15 1
24 8394344 Transcriptional modulation of platelet-activating factor receptor gene expression by cyclic AMP. J Biol Chem 1993 Aug 15 8
25 8478911 Design and modeling of new platelet-activating factor antagonists. 1. Synthesis and biological activity of 1,4-bis(3',4',5'-trimethoxybenzoyl)-2-[[(substituted carbonyl and carbamoyl)oxy]methyl]piperazines. J Med Chem 1993 Apr 16 1
26 8570633 Tissue-specific response of the human platelet-activating factor receptor gene to retinoic acid and thyroid hormone by alternative promoter usage. Proc Natl Acad Sci U S A 1996 Jan 23 1
27 8626474 Mutations of two adjacent amino acids generate inactive and constitutively active forms of the human platelet-activating factor receptor. J Biol Chem 1996 Apr 5 1
28 8645288 Mutation of an aspartate at position 63 in the human platelet-activating factor receptor augments binding affinity but abolishes G-protein-coupling and inositol phosphate production. Biochem Biophys Res Commun 1996 Feb 27 2
29 8892648 Regulation by IL-5 of expression of functional platelet-activating factor receptors on human eosinophils. J Immunol 1996 Nov 1 2
30 8906849 Modulation of human platelet-activating factor receptor gene expression by protein kinase C activation. J Immunol 1996 Nov 15 2
31 9000543 Augmented expression of platelet-activating factor receptor gene by TNF-alpha through transcriptional activation in human monocytes. J Leukoc Biol 1997 Jan 1
32 9034961 Design and modeling of new platelet-activating factor antagonists. 2. Synthesis and biological activity of 1,4-bis-(3',4',5'-trimethoxybenzoyl)-2-alkyl and 2-alkyloxymethylpiperazines. J Lipid Mediat Cell Signal 1997 Jan 1
33 9058812 Transcriptional regulation of platelet-activating factor receptor gene in B lymphoblastoid Ramos cells by TGF-beta. J Immunol 1997 Mar 15 1
34 9109445 Role of platelet-activating factor in Chinese hamster ovary cell responses to cholera toxin. J Clin Invest 1997 Apr 15 1
35 9115222 Role of phospholipase Cbeta3 phosphorylation in the desensitization of cellular responses to platelet-activating factor. J Biol Chem 1997 May 2 2
36 9207433 Bone marrow stroma-derived prolactin is involved in basal and platelet-activating factor-stimulated in vitro erythropoiesis. Blood 1997 Jul 1 1
37 9227410 Eicosanoid production from porcine neutrophils and platelets: differential production with various agonists. Am J Physiol 1997 Jun 2
38 9257915 Dissociation of the effects of the antitumour ether lipid ET-18-OCH3 on cytosolic calcium and on apoptosis. Br J Pharmacol 1997 Aug 1
39 9553132 Multiple signaling pathways of human interleukin-8 receptor A. Independent regulation by phosphorylation. J Biol Chem 1998 Apr 24 1
40 9561175 Monocyte binding to endothelial cells induced by oxidized phospholipids present in minimally oxidized low density lipoprotein is inhibited by a platelet activating factor receptor antagonist. Adv Exp Med Biol 1997 2
41 9603913 Inhibition by platelet-activating factor of Src- and hepatocyte growth factor-dependent invasiveness of intestinal and kidney epithelial cells. Phosphatidylinositol 3'-kinase is a critical mediator of tumor invasion. J Biol Chem 1998 Jun 5 1
42 9668065 Expression of the platelet-activating factor receptor results in enhanced ultraviolet B radiation-induced apoptosis in a human epidermal cell line. J Biol Chem 1998 Jul 24 9
43 9669206 Inhibition of leukotriene B4-induced increase in intracellular calcium ion level of human peripheral blood polymorphonuclear leukocytes by Y-24180, an antagonist of platelet-activating factor receptor. Int J Immunopharmacol 1997 Nov-Dec 3
44 9712066 Activation of the epidermal platelet-activating factor receptor results in cytokine and cyclooxygenase-2 biosynthesis. J Immunol 1998 Aug 15 2
45 9990675 Identification and pharmacological characterization of platelet-activating factor and related 1-palmitoyl species in human inflammatory blistering diseases. Prostaglandins Other Lipid Mediat 1998 Aug 1
46 10067986 PAF binding to a single receptor in corneal epithelium plasma membrane. Invest Ophthalmol Vis Sci 1999 Mar 3
47 10082134 Cobalt chloride-induced signaling in endothelium leading to the augmented adherence of sickle red blood cells and transendothelial migration of monocyte-like HL-60 cells is blocked by PAF-receptor antagonist. J Cell Physiol 1999 Apr 2
48 10320807 The platelet-activating factor receptor antagonist L-659,989 inhibits phospholipase D activity. Biochim Biophys Acta 1999 May 18 1
49 10337026 Lysophosphatidylcholine (LPC) induces proinflammatory cytokines by a platelet-activating factor (PAF) receptor-dependent mechanism. Clin Exp Immunol 1999 May 2
50 10480902 Augmentation of ultraviolet B radiation-induced tumor necrosis factor production by the epidermal platelet-activating factor receptor. J Biol Chem 1999 Sep 17 4