angiotensin converting enzyme 2 ; Homo sapiens






1205 Article(s)
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1 2849100 Two putative active centers in human angiotensin I-converting enzyme revealed by molecular cloning. Proc Natl Acad Sci U S A 1988 Dec 1
2 3027262 Purification and characterization of a peptidyl dipeptidase resembling angiotensin converting enzyme from the electric organ of Torpedo marmorata. J Neurochem 1987 Mar 1
3 8767468 ACAT/CEH and ACEH/LAL: two key enzymes in hepatic cellular cholesterol homeostasis and their involvement in genetic disorders. Z Gastroenterol 1996 Jun 1
4 9461491 A novel peptide-processing activity of insect peptidyl-dipeptidase A (angiotensin I-converting enzyme): the hydrolysis of lysyl-arginine and arginyl-arginine from the C-terminus of an insect prohormone peptide. Biochem J 1998 Feb 15 2
5 10924499 A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase. J Biol Chem 2000 Oct 27 3
6 10969042 A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. Circ Res 2000 Sep 1 2
7 11815627 Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase. J Biol Chem 2002 Apr 26 4
8 12531198 Development of intramolecularly quenched fluorescent peptides as substrates of angiotensin-converting enzyme 2. Anal Biochem 2003 Jan 15 5
9 12914653 Angiotensin-I-converting enzyme and its relatives. Genome Biol 2003 1
10 14609329 Angiotensin-converting enzyme-2 (ACE2): comparative modeling of the active site, specificity requirements, and chloride dependence. Biochemistry 2003 Nov 18 12
11 14670965 A 193-amino acid fragment of the SARS coronavirus S protein efficiently binds angiotensin-converting enzyme 2. J Biol Chem 2004 Jan 30 1
12 15477383 Upregulation of angiotensin-converting enzyme 2 by all-trans retinoic acid in spontaneously hypertensive rats. Hypertension 2004 Dec 2
13 15492138 Structure-based discovery of a novel angiotensin-converting enzyme 2 inhibitor. Hypertension 2004 Dec 1
14 15549171 Angiotensin-converting enzyme-2: a molecular and cellular perspective. Cell Mol Life Sci 2004 Nov 1
15 15983030 Tumor necrosis factor-alpha convertase (ADAM17) mediates regulated ectodomain shedding of the severe-acute respiratory syndrome-coronavirus (SARS-CoV) receptor, angiotensin-converting enzyme-2 (ACE2). J Biol Chem 2005 Aug 26 1
16 16008552 Identification of critical active-site residues in angiotensin-converting enzyme-2 (ACE2) by site-directed mutagenesis. FEBS J 2005 Jul 2
17 16122388 The SARS coronavirus S glycoprotein receptor binding domain: fine mapping and functional characterization. Virol J 2005 Aug 25 1
18 16300161 Management of hospitals in Aceh during the tsunami. World Hosp Health Serv 2005 2
19 16510163 Identification of critical determinants on ACE2 for SARS-CoV entry and development of a potent entry inhibitor. Virology 2006 Jun 20 2
20 16597622 Structure of severe acute respiratory syndrome coronavirus receptor-binding domain complexed with neutralizing antibody. J Biol Chem 2006 Jun 9 2
21 16647014 [Study on up-regulation of the expression of angiotensin-converting enzyme-2 in human umbilical vein endothelial cells by telmisartan]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 2006 Apr 5
22 16730806 Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 interaction. Antiviral Res 2007 May 1
23 16822235 Association study of ACE2 (angiotensin I-converting enzyme 2) gene polymorphisms with coronary heart disease and myocardial infarction in a Chinese Han population. Clin Sci (Lond) 2006 Nov 1
24 16912312 Highly conserved regions within the spike proteins of human coronaviruses 229E and NL63 determine recognition of their respective cellular receptors. J Virol 2006 Sep 2
25 17095582 ACE2 activity is increased in monocyte-derived macrophages from prehypertensive subjects. Nephrol Dial Transplant 2007 Feb 2
26 17473847 Polymorphisms of ACE2 gene are associated with essential hypertension and antihypertensive effects of Captopril in women. Clin Pharmacol Ther 2007 Aug 2
27 17522231 Clathrin-dependent entry of severe acute respiratory syndrome coronavirus into target cells expressing ACE2 with the cytoplasmic tail deleted. J Virol 2007 Aug 2
28 17703127 ACE2: a new target for cardiovascular disease therapeutics. J Cardiovasc Pharmacol 2007 Aug 1
29 17906677 Enhanced angiotensin converting enzyme 2 regulates the insulin/Akt signalling pathway by blockade of macrophage migration inhibitory factor expression. Br J Pharmacol 2008 Jan 2
30 18070603 Calmodulin interacts with angiotensin-converting enzyme-2 (ACE2) and inhibits shedding of its ectodomain. FEBS Lett 2008 Jan 23 1
31 18078750 Thiol-based angiotensin-converting enzyme 2 inhibitors: P1 modifications for the exploration of the S1 subsite. Bioorg Med Chem Lett 2008 Jan 15 2
32 18199653 Aromatic amino acids in the juxtamembrane domain of severe acute respiratory syndrome coronavirus spike glycoprotein are important for receptor-dependent virus entry and cell-cell fusion. J Virol 2008 Mar 1
33 18223028 Functional angiotensin-converting enzyme 2 is expressed in human cardiac myofibroblasts. Exp Physiol 2008 May 3
34 18243695 Thiol-based angiotensin-converting enzyme 2 inhibitors: P1' modifications for the exploration of the S1' subsite. Bioorg Med Chem Lett 2008 Mar 1 1
35 18279660 Lipid rafts are involved in SARS-CoV entry into Vero E6 cells. Biochem Biophys Res Commun 2008 May 2 1
36 18324760 Development of potent and selective phosphinic peptide inhibitors of angiotensin-converting enzyme 2. J Med Chem 2008 Apr 10 7
37 18371537 Expression of ACE and ACE2 in individuals with diabetic kidney disease and healthy controls. Am J Kidney Dis 2008 Apr 2
38 18389211 Urinary mRNA expression of ACE and ACE2 in human type 2 diabetic nephropathy. Diabetologia 2008 Jun 1
39 18403595 Angiotensin II up-regulates angiotensin I-converting enzyme (ACE), but down-regulates ACE2 via the AT1-ERK/p38 MAP kinase pathway. Am J Pathol 2008 May 1
40 18441099 Angiotensin converting enzyme-2 is protective but downregulated in human and experimental lung fibrosis. Am J Physiol Lung Cell Mol Physiol 2008 Jul 1
41 18660448 Angiotensin converting enzyme-2 confers endothelial protection and attenuates atherosclerosis. Am J Physiol Heart Circ Physiol 2008 Oct 1
42 18814896 Importance of cholesterol-rich membrane microdomains in the interaction of the S protein of SARS-coronavirus with the cellular receptor angiotensin-converting enzyme 2. Virology 2008 Nov 25 3
43 19021774 Residues affecting the chloride regulation and substrate selectivity of the angiotensin-converting enzymes (ACE and ACE2) identified by site-directed mutagenesis. FEBS J 2008 Dec 6
44 19141296 Albumin caused the increasing production of angiotensin II due to the dysregulation of ACE/ACE2 expression in HK2 cells. Clin Chim Acta 2009 May 1
45 19164471 The identification of a calmodulin-binding domain within the cytoplasmic tail of angiotensin-converting enzyme-2. Endocrinology 2009 May 6
46 19232015 Activities of angiotensin-converting enzymes ACE1 and ACE2 and inhibition by bioactive peptides in porcine ocular tissues. J Ocul Pharmacol Ther 2009 Feb 5
47 19411314 Ectodomain shedding of angiotensin converting enzyme 2 in human airway epithelia. Am J Physiol Lung Cell Mol Physiol 2009 Jul 5
48 19717501 Angiotensin II reduces membranous angiotensin-converting enzyme 2 in pressurized human aortic endothelial cells. J Renin Angiotensin Aldosterone Syst 2009 Dec 1
49 19927151 Comparison of the long-term effects of candesartan and olmesartan on plasma angiotensin II and left ventricular mass index in patients with hypertension. Hypertens Res 2010 Feb 2
50 20125035 Genetic variants in the apelin system and blood pressure responses to dietary sodium interventions: a family-based association study. J Hypertens 2010 Apr 2