| 1 | 9705271 | Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11, and p95. | J Biol Chem | 1998 Aug 21 |
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| 2 | 10346816 | Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex. | Genes Dev | 1999 May 15 |
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| 3 | 10415333 | Molecular cloning and characterization of splice variants of human RAD50 gene. | Gene | 1999 Jul 22 |
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| 4 | 11029422 | Mre11 and Rad50 from Pyrococcus furiosus: cloning and biochemical characterization reveal an evolutionarily conserved multiprotein machine. | J Bacteriol | 2000 Nov |
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| 5 | 11196187 | Frameshift mutations at coding mononucleotide repeats of the hRAD50 gene in gastrointestinal carcinomas with microsatellite instability. | Cancer Res | 2001 Jan 1 |
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| 6 | 11373271 | Overexpressed human RAD50 exhibits cell death in a p21(WAF1/CIP1)-dependent manner: its potential utility in local gene therapy of tumor. | Cell Growth Differ | 2001 May |
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| 7 | 11429044 | Frameshift mutations at mononucleotide repeats in RAD50 recombinational DNA repair gene in colorectal cancers with microsatellite instability. | Jpn J Cancer Res | 2001 Jun |
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| 8 | 11533665 | Checkpoint activation in response to double-strand breaks requires the Mre11/Rad50/Xrs2 complex. | Nat Cell Biol | 2001 Sep |
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| 9 | 11754637 | An antisense construct of full-length human RAD50 cDNA confers sensitivity to ionizing radiation and alkylating agents on human cell lines. | Radiat Res | 2002 Jan |
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| 10 | 11832209 | The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements. | Cell | 2002 Jan 25 |
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| 11 | 12384589 | DNA end-binding specificity of human Rad50/Mre11 is influenced by ATP. | Nucleic Acids Res | 2002 Oct 15 |
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| 12 | 12509260 | Arsenic-induced Mre11 phosphorylation is cell cycle-dependent and defective in NBS cells. | DNA Repair (Amst) | 2002 Feb 28 |
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| 13 | 12955088 | Differential involvement of the hMRE11/hRAD50/NBS1 complex, BRCA1 and MLH1 in NF-kappaB activation by camptothecin and X-ray. | Oncogene | 2003 Sep 4 |
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| 14 | 14532133 | Requirement of the MRN complex for ATM activation by DNA damage. | EMBO J | 2003 Oct 15 |
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| 15 | 14550546 | Nitric oxide-dependent cytoskeletal changes and inhibition of endothelial cell migration contribute to the suppression of angiogenesis by RAD50 gene transfer. | FEBS Lett | 2003 Oct 9 |
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| 16 | 14657032 | The Mre11 complex is required for ATM activation and the G2/M checkpoint. | EMBO J | 2003 Dec 15 |
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| 17 | 14698290 | The rad50 signature motif: essential to ATP binding and biological function. | J Mol Biol | 2004 Jan 23 |
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| 18 | 14710187 | MlaA, a hexameric ATPase linked to the Mre11 complex in archaeal genomes. | EMBO Rep | 2004 Jan |
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| 19 | 15039997 | Intracellular redistribution and modification of proteins of the Mre11/Rad50/Nbs1 DNA repair complex following irradiation and heat-shock. | J Cell Physiol | 2004 May |
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| 20 | 15048091 | Mutations of an intronic repeat induce impaired MRE11 expression in primary human cancer with microsatellite instability. | Oncogene | 2004 Apr 8 |
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| 21 | 15476893 | Nijmegen breakage syndrome and DNA double strand break repair by NBS1 complex. | Adv Biophys | 2004 |
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| 22 | 15493328 | Nijmegen breakage syndrome and DNA double strand break repair by NBS1 complex. | Adv Biophys | 2004 |
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| 23 | 15589152 | Chromosome fragmentation after induction of a double-strand break is an active process prevented by the RMX repair complex. | Curr Biol | 2004 Dec 14 |
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| 24 | 15741314 | Arginine methylation of MRE11 by PRMT1 is required for DNA damage checkpoint control. | Genes Dev | 2005 Mar 15 |
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| 25 | 15908798 | The Mre11/Rad50/Nbs1 complex and its role as a DNA double-strand break sensor for ATM. | Cell Cycle | 2005 Jun |
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| 26 | 16025146 | Impaired nonhomologous end-joining in mismatch repair-deficient colon carcinomas. | Lab Invest | 2005 Sep |
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| 27 | 16542220 | Impairment of double-strand breaks repair and aberrant splicing of ATM and MRE11 in leukemia-lymphoma cell lines with microsatellite instability. | Cancer Sci | 2006 Mar |
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| 28 | 16879433 | Double-strand breaks trigger MRX- and Mec1-dependent, but Tel1-independent, checkpoint activation. | FEMS Yeast Res | 2006 Aug |
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| 29 | 16928817 | Vorinostat, a histone deacetylase inhibitor, enhances the response of human tumor cells to ionizing radiation through prolongation of gamma-H2AX foci. | Mol Cancer Ther | 2006 Aug |
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| 30 | 17121922 | The Mre11/Rad50/Nbs1 complex interacts with the mismatch repair system and contributes to temozolomide-induced G2 arrest and cytotoxicity. | Mol Cancer Ther | 2006 Nov |
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| 31 | 17369853 | Pol eta is required for DNA replication during nucleotide deprivation by hydroxyurea. | Oncogene | 2007 Aug 23 |
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| 32 | 17386254 | Learning our ABCs: Rad50 directs MRN repair functions via adenylate kinase activity from the conserved ATP binding cassette. | Mol Cell | 2007 Mar 23 |
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| 33 | 17426050 | Dimerization of the Rad50 protein is independent of the conserved hook domain. | Mutagenesis | 2007 Jul |
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| 34 | 17431132 | Enhanced phosphorylation of Nbs1, a member of DNA repair/checkpoint complex Mre11-RAD50-Nbs1, can be targeted to increase the efficacy of imatinib mesylate against BCR/ABL-positive leukemia cells. | Blood | 2007 Jul 15 |
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| 35 | 17690534 | Inhibition of potential lethal damage repair and related gene expression after carbon-ion beam irradiation to human lung cancer grown in nude mice. | J Radiat Res | 2007 Sep |
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| 36 | 17700070 | Replication protein A is required for etoposide-induced assembly of MRE11/RAD50/NBS1 complex repair foci. | Cell Cycle | 2007 Oct 1 |
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| 37 | 17879257 | Gene expression changes associated with altered growth and differentiation in benzo[a]pyrene or arsenic exposed normal human epidermal keratinocytes. | J Appl Toxicol | 2008 May |
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| 38 | 18262646 | Is defect in phosphorylation of Nbs1 responsible for high radiosensitivity of T-lymphocyte leukemia cells MOLT-4? | Leuk Res | 2008 Aug |
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| 39 | 18596698 | Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity. | EMBO J | 2008 Jul 23 |
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| 40 | 18632984 | Transcription-coupled DNA double-strand breaks are mediated via the nucleotide excision repair and the Mre11-Rad50-Nbs1 complex. | Mol Biol Cell | 2008 Sep |
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| 41 | 18645678 | Adriamycin induces H2AX phosphorylation in human spermatozoa. | Asian J Androl | 2008 Sep |
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| 42 | 18829552 | ATM and the Mre11-Rad50-Nbs1 complex respond to nucleoside analogue-induced stalled replication forks and contribute to drug resistance. | Cancer Res | 2008 Oct 1 |
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| 43 | 18852132 | Role of histone deacetylase inhibitor-induced reactive oxygen species and DNA damage in LAQ-824/fludarabine antileukemic interactions. | Mol Cancer Ther | 2008 Oct |
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| 44 | 18941461 | Microsatellite instability due to hMLH1 deficiency is associated with increased cytotoxicity to irinotecan in human colorectal cancer cell lines. | Br J Cancer | 2008 Nov 18 |
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| 45 | 19308707 | RAD50, an SMC family member with multiple roles in DNA break repair: how does ATP affect function? | Chromosome Res | 2009 |
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| 46 | 19487811 | Molecular disruption of RAD50 sensitizes human tumor cells to cisplatin-based chemotherapy. | J Clin Invest | 2009 Jul |
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| 47 | 19643248 | Head and neck squamous cell carcinoma targeted chemosensitization. | Otolaryngol Head Neck Surg | 2009 Aug |
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| 48 | 19866438 | Correlation of aberrant expression of p53, Rad50, and cyclin-E proteins with microsatellite instability in gallbladder adenocarcinomas. | Genet Mol Res | 2009 Oct 6 |
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| 49 | 20064462 | CtIP links DNA double-strand break sensing to resection. | Mol Cell | 2009 Dec 25 |
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| 50 | 20447876 | Delineation of WRN helicase function with EXO1 in the replicational stress response. | DNA Repair (Amst) | 2010 Jul 1 |
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