cytochrome b-245 alpha chain ; Homo sapiens






218 Article(s)
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1 7517218 CD34+ peripheral blood progenitors as a target for genetic correction of the two flavocytochrome b558 defective forms of chronic granulomatous disease. Blood 1994 Jul 1 1
2 7938008 Assembly of the phagocyte NADPH oxidase: binding of Src homology 3 domains to proline-rich targets. Proc Natl Acad Sci U S A 1994 Oct 25 1
3 7964505 156Pro-->Gln substitution in the light chain of cytochrome b558 of the human NADPH oxidase (p22-phox) leads to defective translocation of the cytosolic proteins p47-phox and p67-phox. J Exp Med 1994 Dec 1 3
4 8245781 Restitution of superoxide generation in autosomal cytochrome-negative chronic granulomatous disease (A22(0) CGD)-derived B lymphocyte cell lines by transfection with p22phax cDNA. J Exp Med 1993 Dec 1 1
5 8634451 Cloning of murine gp91phox cDNA and functional expression in a human X-linked chronic granulomatous disease cell line. Blood 1996 Mar 1 2
6 8650211 PR-39, a proline-rich antibacterial peptide that inhibits phagocyte NADPH oxidase activity by binding to Src homology 3 domains of p47 phox. Proc Natl Acad Sci U S A 1996 Jun 11 1
7 9032440 Analysis of glycosylation sites on gp91phox, the flavocytochrome of the NADPH oxidase, by site-directed mutagenesis and translation in vitro. Biochem J 1997 Feb 1 3
8 9060453 Immunoelectron microscopy shows a clustered distribution of NADPH oxidase components in the human neutrophil plasma membrane. J Leukoc Biol 1997 Mar 2
9 9296450 Detection of superoxide and NADPH oxidase in porcine articular chondrocytes. Free Radic Biol Med 1997 1
10 9447831 Expression of NADPH oxidase is induced by all-trans retinoic acid but not by phorbol myristate acetate and 1,25 dihydroxyvitamin D3 in the human promyelocytic cell line NB4. Leukemia 1997 Dec 1
11 9740615 Role of NADH/NADPH oxidase-derived H2O2 in angiotensin II-induced vascular hypertrophy. Hypertension 1998 Sep 2
12 9794433 Nicotinamide-adenine dinucleotide phosphate oxidase assembly and activation in EBV-transformed B lymphoblastoid cell lines of normal and chronic granulomatous disease patients. J Immunol 1998 Nov 1 1
13 9856476 A novel mutation at a probable heme-binding ligand in neutrophil cytochrome b558 in atypical X-linked chronic granulomatous disease. Hum Genet 1998 Oct 3
14 10393079 The mechanism of activation of NADPH oxidase in the cell-free system: the activation process is primarily catalytic and not through the formation of a stoichiometric complex. Biochem J 1999 Jul 15 1
15 10440830 Relationship of the C242T p22phox gene polymorphism to angiographic coronary artery disease and endothelial function. Am J Med Genet 1999 Sep 3 2
16 10720412 NADH oxidase activation is involved in arsenite-induced oxidative DNA damage in human vascular smooth muscle cells. Circ Res 2000 Mar 17 4
17 10865844 Role of the vascular NADH/NADPH oxidase system in atherosclerosis. Ann N Y Acad Sci 2000 May 2
18 10928986 Oxidative stress and expression of p22phox are involved in the up-regulation of tissue factor in vascular smooth muscle cells in response to activated platelets. FASEB J 2000 Aug 2
19 10946846 Lipophilic HMG-CoA reductase inhibitor has an anti-inflammatory effect: reduction of MRNA levels for interleukin-1beta, interleukin-6, cyclooxygenase-2, and p22phox by regulation of peroxisome proliferator-activated receptor alpha (PPARalpha) in primary endothelial cells. Life Sci 2000 Jul 14 6
20 11023926 Functional effect of the C242T polymorphism in the NAD(P)H oxidase p22phox gene on vascular superoxide production in atherosclerosis. Circulation 2000 Oct 10 4
21 11172467 The ligands/activators for peroxisome proliferator-activated receptor alpha (PPARalpha) and PPARgamma increase Cu2+,Zn2+-superoxide dismutase and decrease p22phox message expressions in primary endothelial cells. Metabolism 2001 Jan 3
22 11241298 Mechanisms of expression of NADPH oxidase components in human cultured monocytes: role of cytokines and transcriptional regulators involved. Eur J Immunol 2001 Mar 1
23 11339504 Evaluation of the expression of NADPH oxidase components during maturation of HL-60 clone 15 cells to eosinophilic lineage. Inflamm Res 2001 Mar 1
24 11434692 Thrombin-induced MCP-1 expression involves activation of the p22phox-containing NADPH oxidase in human vascular smooth muscle cells. Thromb Haemost 2001 Jun 3
25 11510094 [Genetic variation of NADPH/NADH oxidase and susceptibility to diffuse panbronchiolitis (DPB) and chronic obstructive pulmonary disease (COPD)]. Nihon Kokyuki Gakkai Zasshi 2001 May 1
26 11711515 Flow pulsatility is a critical determinant of oxidative stress in endothelial cells. Hypertension 2001 Nov 2
27 12037698 The C242T-polymorphism of the NADPH/NADH oxidase gene p22phox subunit is not associated with pre-eclampsia. J Hum Hypertens 2002 Jun 1
28 12059072 Rapid detection of polymorphisms of the nitric oxide cascade. Clin Chem Lab Med 2002 Apr 1
29 12440767 The superoxide-generating NADPH oxidase: structural aspects and activation mechanism. Cell Mol Life Sci 2002 Sep 1
30 12512689 Mechanisms of superoxide production in human blood vessels: relationship to endothelial dysfunction, clinical and genetic risk factors. J Physiol Pharmacol 2002 Dec 2
31 12639216 The C242T p22phox polymorphism and endothelium-dependent vasodilation in subjects with hypercholesterolaemia. Clin Sci (Lond) 2003 Jul 3
32 12654483 Activation of NAD(P)H oxidase by lipid hydroperoxides: mechanism of oxidant-mediated smooth muscle cytotoxicity. Free Radic Biol Med 2003 Apr 1 5
33 12686516 NOX5 NAD(P)H oxidase regulates growth and apoptosis in DU 145 prostate cancer cells. Am J Physiol Cell Physiol 2003 Aug 1
34 12690038 Role of redox signaling in the autonomous proliferative response of endothelial cells to hypoxia. Circ Res 2003 May 16 2
35 12772776 Inhibition of the neutrophil NADPH oxidase by adenosine is associated with increased movement of flavocytochrome b between subcellular fractions. Inflammation 2003 Feb 2
36 12805076 Interaction of oxidative stress and inflammatory response in coronary plaque instability: important role of C-reactive protein. Arterioscler Thromb Vasc Biol 2003 Aug 1 2
37 12807699 NAD(P)H oxidase mediates the endothelial barrier dysfunction induced by TNF-alpha. Am J Physiol Lung Cell Mol Physiol 2004 Jan 2
38 12877653 Investigation of the C242T polymorphism of NAD(P)H oxidase p22 phox gene and ischaemic heart disease using family-based association methods. Clin Sci (Lond) 2003 Dec 1
39 12905852 [Progress in the studies on the relationship between the polymorphism of P22phox gene and coronary heart disease]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2002 Feb 1
40 14561241 Lack of evidence for association of high altitude pulmonary edema and polymorphisms of the NO pathway. High Alt Med Biol 2003 Fall 1
41 14578299 Intermittent high glucose enhances apoptosis related to oxidative stress in human umbilical vein endothelial cells: the role of protein kinase C and NAD(P)H-oxidase activation. Diabetes 2003 Nov 1
42 14652666 Role of p22phox in angiotensin II and platelet-derived growth factor AA induced activator protein 1 activation in vascular smooth muscle cells. J Mol Med (Berl) 2004 Jan 4
43 14679084 Nicotinamide adenine dinucleotide phosphate oxidase (NADPH oxidase) P22 Phox C242T gene polymorphism in type 1 diabetes. Ann N Y Acad Sci 2003 Nov 3
44 14968555 [Genetic risk factors for ischemic cerebrovascular disease--analysis on fifteen candidate prothrombotic gene polymorphisms in the Japanese population]. Rinsho Byori 2004 Jan 1
45 15078863 C242T CYBA polymorphism of the NADPH oxidase is associated with reduced respiratory burst in human neutrophils. Hypertension 2004 Jun 2
46 15085064 Effect of manidipine on gene expression and protein level of oxidative stress-related proteins: p22phox and HO-1: relevance for antihypertensive and anti-remodeling effects. J Cardiovasc Pharmacol 2004 Apr 1
47 15210651 Functional effect of the p22phox -930A/G polymorphism on p22phox expression and NADPH oxidase activity in hypertension. Hypertension 2004 Aug 1
48 15322091 Direct interaction of the novel Nox proteins with p22phox is required for the formation of a functionally active NADPH oxidase. J Biol Chem 2004 Oct 29 3
49 15461271 [Study on the relationship between the polymorphism of P22phox C242T, vitamin E and coronary heart disease]. Wei Sheng Yan Jiu 2004 Jul 6
50 15507762 Molecular mechanism underlying activation of superoxide-producing NADPH oxidases: roles for their regulatory proteins. Jpn J Infect Dis 2004 Oct 1